One new 14-membered frangulanine-type cyclopeptide alkaloid, oxyphyl line-A (1) has been isolated from the stem bark of Zizyphus oxyphylla together with the known 13-membered cyclopeptide, nummularine R (2). The structure was established on the basis of spectral studies particularly 2D NMR.

Download full-text PDF

Source
http://dx.doi.org/10.1080/14786410600906574DOI Listing

Publication Analysis

Top Keywords

cyclopeptide alkaloid
8
zizyphus oxyphylla
8
14-membered cyclopeptide
4
alkaloid zizyphus
4
oxyphylla 14-membered
4
14-membered frangulanine-type
4
frangulanine-type cyclopeptide
4
alkaloid oxyphyl
4
oxyphyl line-a
4
line-a isolated
4

Similar Publications

TREATMENT OUTCOMES OF GESTATIONAL TROPHOBLASTIC DISEASE, EXPERIENCE FROM SAUDI ARABIA.

J Ayub Med Coll Abbottabad

November 2024

Department of Medical Oncology, Prince Sultan Military Medical City, Riyadh-Saudi Arabia.

Background: This research aims to assess the treatment outcomes and chemotherapy duration required for the normalization of Human chorionic gonadotropin (HCG) levels in patients diagnosed with Gestational Trophoblastic Neoplasia (GTN), encompassing both benign and malignant forms of the condition.

Methods: This retrospective study included GTD patients treated with chemotherapy in a single oncology clinic from January 2016 to May 2022. Clinical data were gathered from electronic records of the patients.

View Article and Find Full Text PDF

In this report, we describe a fluorescent assay for the detection of six marine toxins in water. The mechanism of detection is based on a duplex-to-complex structure-switching approach. The six aptamers specific to the targeted cyanotoxins were conjugated to a fluorescent dye, carboxyfluorescein (FAM).

View Article and Find Full Text PDF

Bloom-forming planktonic Microcystis and benthic Oscillatoria-induced oxidative stress and inflammatory responses in juvenile silver carp and bighead carp.

Toxicon

January 2025

Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing, 210008, China; State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing, 210008, China.

As global warming and water eutrophication, the multiple proliferation of harmful cyanobacteria can form algal blooms and cause serious ecological problems. In recent years, the large-scale and persistent cyanobacterial blooms occur frequently worldwide and have attracted widespread attention due to the harmful impacts. Among these harmful bloom-forming cyanobacteria, the ecological and toxicological impacts of planktonic cyanobacteria have been extensively studied.

View Article and Find Full Text PDF

Multi-class cyanobacterial toxin analysis using hydrophilic interaction liquid chromatography-mass spectrometry.

J Chromatogr A

December 2024

Biotoxin Metrology, National Research Council Canada, 1411 Oxford St., Halifax, NS, B3H 3Z1, Canada.

Cyanobacteria produce diverse classes of toxins including microcystins, nodularins, anatoxins, cylindrospermopsins and saxitoxins, encompassing a range of chemical properties and mechanisms of toxicity. Comprehensive analysis of these toxins in cyanobacterial, environmental and biological samples generally requires multiple methods of extraction and analysis. In this work, a method was developed for the major classes of cyanotoxins, which comprised of a three-step liquid-solid extraction method using 75 % CHCN with 0.

View Article and Find Full Text PDF

Some of the most commonly identified freshwater toxins are anatoxin-a (ATX-a), cylindrospermopsin (CYN), and microcystin-LR (MC-LR). The aim of this paper was to compare different methods of extracting and concentrating these cyanotoxins and check the impact of selected physical factors on the accumulation of biomass of Dolichospermum flos-aquae, Microcystis aeruginosa, and Raphidiopsis raciborskii. The effect of different cyanobacteria cultivation conditions on the amount of cyanotoxins synthesized showed no significant changes over time in the average concentration of all tested toxins in the medium compared to the control.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!