The objective of this research was to study the factors that relate to the effectiveness of upper-room ultraviolet germicidal irradiation for inactivating airborne microorganisms. The work was conducted in a room-sized chamber designed and furnished for investigations of this nature. Nebulized Serratia marcescens, Bacillus subtilis spores, and vaccinia virus were used as test aerosols. Most data were collected from steady-state experiments comparing the number of viable organisms in the chamber air remaining with UV lamps turned on to the number with UV lamps turned off, but some decay experiments were conducted to compare the two methods. UV power level had a strong influence but was fully effective only in the presence of air mixing that produced vigorous vertical air currents. A conclusion of the study is that an upper-room ultraviolet installation is a complex system that requires careful integration of UV luminaires, UV power, and room ventilation arrangements.
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http://dx.doi.org/10.1080/15459620701271693 | DOI Listing |
J Environ Health Sci Eng
December 2024
Faculty of Engineering, Built Environment & IT, SEGi University, Petaling Jaya, 47810 Selangor Malaysia.
The Covid 19 pandemic has significantly affected the health, economy, and social impact of humanity. The continuous mutations of the virus variants have accelerated the demand for scientific research on disinfection techniques for a safer indoor environment. Among all the available surface disinfection techniques, ultraviolet germicidal irradiance at 254 nm wavelength has been proven for its disinfection efficacy; however, its usage is limited to unoccupied conditions due to the risk of ultraviolet exposure.
View Article and Find Full Text PDFJ Hazard Mater
November 2024
School of Energy and Environment, City University of Hong Kong, Tat Chee Avenue, Hong Kong. Electronic address:
The air disinfection efficacy of upper-room 222 nm Far-UVC was experimentally investigated in a real-size chamber under well-mixed air conditions. Two bacteria (Escherichia coli, Staphylococcus epidermidis) and two bacteriophages (MS2, and P22) were selected for the test. The study considered different lamp source arrangements, including single and double sources, stationary and rotating operating modes, and an overlapping mode with a 45° irradiation angle.
View Article and Find Full Text PDFJ Hazard Mater
September 2024
Department of Power Engineering, North China Electric Power University, Baoding, Hebei 071003, PR China. Electronic address:
Multi-compartment dental clinics present significant airborne cross-infection risks. Upper-room ultraviolet germicidal irradiation (UR-UVGI) system have shown promise in preventing airborne pathogens, but its available application data are insufficient in multi-compartment dental clinics. Therefore, the UR-UVGI system's performance in a multi-compartment dental clinic was comprehensively evaluated in this study.
View Article and Find Full Text PDFSci Rep
July 2024
Signify, High Tech Campus 7, 5656AE, Eindhoven, The Netherlands.
The recent COVID-19 pandemic has raised interest in efficient air disinfection solutions. The application of germicidal ultraviolet (GUV) irradiation is an excellent contender to prevent airborne transmission of COVID-19, as well as other existing and future infectious airborne diseases. While GUV has already been proven effective in inactivating SARS-CoV-2, quantitative data on UV susceptibility and dose requirements, needed to predict and optimize the performance of GUV solutions, is still limited.
View Article and Find Full Text PDFAm J Infect Control
September 2024
Division of Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic, Rochester, MN.
Background: The coronavirus disease 2019 pandemic has highlighted the need for effective infection control in outpatient health care settings. Germicidal ultraviolet-C (GUV) light, known for inactivating microorganisms by damaging their deoxyribonucleic acid or ribonucleic acid, offers a potential solution. This study examines the efficacy of GUV air disinfection systems in real-world outpatient environments.
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