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[Ga68] DOTATATE PET/MRI-guided radiosurgical treatment planning and response assessment in meningiomas.
Neuro Oncol
August 2024
Department of Radiation Oncology, Weill Cornell Medicine, New York, New York, USA.
Background: Our purpose was to determine the utility of [68Ga]-DOTATATE PET/MRI in meningioma response assessment following radiosurgery.
Methods: Patients with meningioma prospectively underwent postoperative DOTATATE PET/MRI. Co-registered PET and gadolinium-enhanced T1-weighted MRI were employed for radiosurgery planning.
Intraoperative Real-Time Near-Infrared Image-Guided Surgery to Identify Intracranial Meningiomas Microscope.
Front Neurosci
May 2022
Department of Neurosurgery, Fujita Health University, Toyoake, Japan.
Article Synopsis
- * In a trial involving 15 patients, the delayed-window ICG technique successfully visualized meningiomas in 12 cases after administering ICG, illustrating its effectiveness with a mean signal-to-background ratio indicating good tumor visibility.
- * The study found that delayed-window ICG has high sensitivity (94%) but lower specificity (38%), and highlights correlations between tumor visibility, gadolinium MRI signals, and blood-brain barrier permeability, suggesting potential for improved surgical outcomes. *
Occipital to Angular Artery Bypass for Post-irradiation Ischemia: 3-Dimensional Operative Video.
Oper Neurosurg (Hagerstown)
March 2020
Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida.
The authors present a 3D surgical video of a direct occipital to angular artery bypass for cerebral revascularization in the setting of Post-irradiation middle cerebral artery stenosis and symptomatic hypoperfusion. The case refers to a 50-yr-old woman with a history of an unresectable residual skull base meningioma, previously approached through a left frontotemporal craniotomy, and treated with radiation 5 yr prior to presentation. She now presented with right-sided limb shaking transient ischemic attacks and aphasia, along with evidence of left middle cerebral artery territory ischemia.
View Article and Find Full Text PDFHypofractionated high-energy proton-beam irradiation is an alternative treatment for WHO grade I meningiomas.
Acta Neurochir (Wien)
December 2017
Department of Immunology, Genetics and Pathology, Experimental and Clinical Oncology, Uppsala University, Uppsala University Hospital, 751 85, Uppsala, Sweden.
Background: Radiation treatment is commonly employed in the treatment of meningiomas. The aim of this study was to evaluate the effectiveness and safety of hypofractionated high-energy proton therapy as adjuvant or primary treatment for WHO grade I meningiomas.
Method: A total of 170 patients who received irradiation with protons for grade I meningiomas between 1994 and 2007 were included in the study.
Radiation-induced anaplastic ependymoma mimicking a skull base meningioma: A case report.
Exp Ther Med
February 2016
Clinical Neurophysiology Unit, Neuromed Institute IRCCS, Pozzilli I-86077, Italy.
The present study describes the case of a 63-year-old woman presenting with headache, dizziness and vomiting due to a an ovoid mass in the left pre-bulbar cistern, apparently arising from the lower clivus and the foramen magnum. The clinical history revealed the subtotal removal of a right cerebellar low-grade glioma 15 years previously and subsequent conventional 60-Gy radiotherapy. Notably, following gross total resection, histopathological examination showed microscopic features that resulted in a diagnosis of anaplastic ependymoma.
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