Background: To develop Canadian guidelines for the management of primary open-angle glaucoma and provide a quick and practical reference for physicians in the office setting.
Methods: A Canadian Glaucoma Strategy began with a review of the literature and existing guidelines, as well as consultation with glaucoma specialists and general ophthalmologists across Canada. The resulting information was assessed by a panel of glaucoma experts and general ophthalmologists at the Canadian Glaucoma Strategy Forum to distill what was learned and construct the algorithms of care.
Results: A Canadian Glaucoma Strategy was developed in 4 algorithms. First, patients are diagnosed on the basis of risk assessment and clinical findings. The staging algorithm is designed to determine the disease stage, while the treatment and follow-up algorithms focus on control of intraocular pressure and continuing patient follow-up.
Interpretation: A Canadian Glaucoma Strategy is a practical series of algorithms that can be at hand in the office setting, providing the general ophthalmologist with an up-to-date guide for the management of patients with glaucoma concerns.
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JAMA Ophthalmol
November 2024
Queensland Institute of Medical Research Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Importance: Early detection of glaucoma is essential to timely monitoring and treatment, and primary open-angle glaucoma risk can be assessed by measuring intraocular pressure (IOP) or optic nerve head vertical cup-disc ratio (VCDR). Polygenic risk scores (PRSs) could provide a link between genetic effects estimated from genome-wide association studies (GWASs) and clinical applications to provide estimates of an individual's genetic risk by combining many identified variants into a score.
Objective: To construct IOP and VCDR PRSs with clinically relevant predictive power.
Can J Ophthalmol
September 2024
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada.
Can J Ophthalmol
July 2024
Department of Surgery, Section of Ophthalmology, University of Calgary, Calgary, AB; Department of Surgery, Section of Ophthalmology, University of Calgary, Calgary, AB.
Objective: To analyse assessment and management patterns of intraocular foreign body (IOFB) injuries in an urban Canadian setting, providing valuable clinical insights to contextualize management.
Methods: Single-surgeon retrospective chart review from January 2002 to January 2023 examining IOFB patient demographics, investigations, treatments, complications, and best-corrected visual acuity (BCVA).
Results: This study evaluated IOFBs in 32 eyes from 31 patients (96.
J Glaucoma
September 2024
Department of Ophthalmology, School of Medicine, University of North Carlina at Chapel Hill, Chapel Hill, NC.
Prcis: Initial presentation of glaucoma at a major eye clinic mostly features advanced disease with a high proportion of blindness. This is likely a microcosm of a nationwide issue requiring concerted strategies to detect glaucoma early.
Purpose: To characterize the severity stage of new glaucoma patients in Congolese attending a university eye clinic.
Can J Ophthalmol
May 2024
School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON; Ottawa Hospital Research Institute, Ottawa, ON; Bruyère Research Institute, Ottawa, ON. Electronic address:
Objective: To examine the employment status of those with and without visual impairment and eye disease and to examine the association between visual impairment and eye disease and a reduction in income over a 3-year period.
Design: Population-based prospective cohort study.
Participants: A total of 12,174 nonretired participants aged 45-64 years old in the Canadian Longitudinal Study on Aging.
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