Objective: To evaluate the effects of the polypeptide growth factors on the periodontal ligament cell (PDLC) based on a comprehensive review on the literature concerned.
Methods: The recent literature related to the effects of the polypeptide growth factors on the PDLC were extensively and comprehensively reviewed and a corresponding evaluation was made.
Results: The proliferation and the multi-directional differentiation of the PDLC were found to be the basis for the regeneration of the periodontal tissues. The effects of the polypeptide growth factors on the function of the PDLC became a hot issue of the research on the regeneration of the periodontal tissues. The polypeptide growth factors were found to play an important role in the migration, growth, proliferation, differentiation, and synthesis of protein and matrix of the PDLC.
Conclusion: The polypeptide growth factors can be used in the periodontal regeneration treatment, but a further research is still required to improve this kind of treatment.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Corneal Keratocytes, Fibroblasts, and Myofibroblasts Exhibit Distinct Transcriptional Profiles In Vitro.
Invest Ophthalmol Vis Sci
March 2025
Department of Bioengineering, University of Texas at Dallas, Richardson, Texas, United States.
Purpose: After stromal injury to the cornea, the release of growth factors and pro-inflammatory cytokines promotes the activation of quiescent keratocytes into a migratory fibroblast and/or fibrotic myofibroblast phenotype. Persistence of the myofibroblast phenotype can lead to corneal fibrosis and scarring, which are leading causes of blindness worldwide. This study aims to establish comprehensive transcriptional profiles for cultured corneal keratocytes, fibroblasts, and myofibroblasts to gain insights into the mechanisms through which these phenotypic changes occur.
View Article and Find Full Text PDFCorrelation between periodontal status, whole salivary interleukin-1beta levels and oral yeasts carriage among individuals with varying ranges of body mass index.
Acta Odontol Scand
March 2025
Department of General Dental Practice, Faculty of Dentistry, Kuwait University, Safat, Kuwait.
The aim was to assess the correlation between periodontal status, whole salivary interleukin-1 beta (IL-1β) levels and oral yeasts carriage (OYC) among individuals with varying ranges of body mass index (BMI). Material and method: The weight, waist circumference (WC), and height of individuals were assessed. Participants were categorized into three groups: Group-1 - normal weight (18.
View Article and Find Full Text PDFCriteria and prognostic factors for survival and success rates for autotransplantation in the area of first and second molars.
Swiss Dent J
March 2025
Riga Stradiņš University, Faculty of Dentistry.
Autotransplantation of immature third molars is an effective treatment option, offering high success rates, minimal complications, and notable improvements in occlusal function and dental aesthetics. This study aims to review and evaluate the available evidence specifically on the survival and success rates of immature autotransplanted third molars and to identify prognostic factors that influence these outcomes. A comprehensive search was conducted in the Elsevier Journals (ScienceDirect), MEDLINE (PubMed), and Dentistry & Oral Sciences Source (EBSCOhost) databases up to May 2024.
View Article and Find Full Text PDFThe Preparation of Robust Gully-like Surface of Stainless Steel Fiber-Bonded TFPA-TTA-COF with Nano Pores for Solid-Phase Microextraction of Phenolic Compounds in Water.
Nanomaterials (Basel)
February 2025
Department of Environmental Science and Engineering, North China Electric Power University, Baoding 071003, China.
In this paper, a novel robust TFPA-TTA-COF coating with nano pores was grafted to the gully-like surface of stainless steel fibers (GS-SSF). The GS-SSF were prepared using a two-step electrochemical etching method, and the covalent organic framework (COF) TFPA-TTA-COF coating was chemically bonded to the gully-like surface via in situ growth. The prepared metal fibers were applied as the headspace solid-phase microextraction (HS-SPME) fibers and combined with gas chromatography (GC) to develop a detection method for phenolic compounds (PCs) in water.
View Article and Find Full Text PDFSelective Azapeptide CD36 Ligand MPE-298 Regulates oxLDL-LOX-1-Mediated Inflammation and Mitochondrial Oxidative Stress in Macrophages.
Cells
March 2025
Faculté de Pharmacie, Université de Montréal, Montréal, QC H3C 3J7, Canada.
Macrophage mitochondrial dysfunction, caused by oxidative stress, has been proposed as an essential event in the progression of chronic inflammation diseases, such as atherosclerosis. The cluster of differentiation-36 (CD36) and lectin-like oxLDL receptor-1 (LOX-1) scavenger receptors mediate macrophage uptake of oxidized low-density lipoprotein (oxLDL), which contributes to mitochondrial dysfunction by sustained production of mitochondrial reactive oxygen species (mtROS), as well as membrane depolarization. In the present study, the antioxidant mechanisms of action of the selective synthetic azapeptide CD36 ligand MPE-298 have been revealed.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!