We report a three-channel, spectrally beam-combined (SBC), 1 mum fiber laser that produces 522 W of average power with near-diffraction-limited (M2 ~ 1.2) beam quality. The laser features a SBC power combining efficiency of 93%, versatile master-oscillator, power-amplifier fiber channels with up to 260 W of narrow-band, polarized, and near-diffraction-limited output that is tunable over nearly the entire 1 micro m Yb(3+) gain bandwidth, and excellent prospects for significant power scaling. To our knowledge, these results represent the highest beam quality and average power achieved to date for a beam-combined fiber laser system.
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http://dx.doi.org/10.1364/ol.32.000349 | DOI Listing |
BMC Nurs
January 2025
Faculty of Applied Medical Sciences in Alnamas, University of Bisha, 255, Al Nakhil, Al-Namas, 67714, Saudi Arabia.
Background: One of the best ways to impart important skills to trainees is through simulation-based training, which is more reliable than the conventional clinical examination method. It is used in pediatric nursing training to allow nurses to practice and improve their clinical and conversational skills during an actual child encounter. A heel-prick is a complex psychomotor task that requires skill and knowledge from the pediatric nurse performing the procedure while applying for the National Newborn Screening Program.
View Article and Find Full Text PDFTrials
January 2025
Department of Electrical and Computer Engineering, Princeton University, Princeton, 08544, NJ, USA.
Background: Phase-3 clinical trials provide the highest level of evidence on drug safety and effectiveness needed for market approval by implementing large randomized controlled trials (RCTs). However, 30-40% of these trials fail mainly because such studies have inadequate sample sizes, stemming from the inability to obtain accurate initial estimates of average treatment effect parameters.
Methods: To remove this obstacle from the drug development cycle, we present a new algorithm called Trend-Adaptive Design with a Synthetic-Intervention-Based Estimator (TAD-SIE) that powers a parallel-group trial, a standard RCT design, by leveraging a state-of-the-art hypothesis testing strategy and a novel trend-adaptive design (TAD).
Neural Netw
January 2025
School of Computer Science, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.
Learning from data streams that emerge from nonstationary environments has many real-world applications and poses various challenges. A key characteristic of such a task is the varying nature of the underlying data distributions over time (concept drifts). However, the most common type of data stream learning approach are ensemble approaches, which involve the training of multiple base learners.
View Article and Find Full Text PDFPLoS One
January 2025
Suliman S. Olayan School of Business (OSB), American University of Beirut (AUB), Beirut, Lebanon.
Historically, the film industry has been male-dominated both in front of and behind the camera, resulting in a longstanding gender imbalance in storytelling and representation. This legacy of male-centric narratives may unconsciously influence critics' expectations and judgments. Existing literature suggests that negative critiques in movie reviews can significantly impact actors' earnings by diminishing a film's commercial prospects.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
University of Oregon, Department of Physics and Materials Science Institute, Eugene, Oregon 97403, USA.
We consider many-particle diffusion in one spatial dimension modeled as "random walks in a random environment." A shared short-range space-time random environment determines the jump distributions that drive the motion of the particles. We determine universal power laws for the environment's contribution to the variance of the extreme first passage time and extreme location.
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