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Influence of lung function on macro- and micro-structural brain changes in mid- and late-life.
Int J Surg
January 2025
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Introduction: Lung function has been associated with cognitive decline and dementia, but the extent to which lung function impacts brain structural changes remains unclear. We aimed to investigate the association of lung function with structural macro- and micro-brain changes across mid- and late-life.
Methods: The study included a total of 37 164 neurologic disorder-free participants aged 40-70 years from the UK Biobank, who underwent brain MRI scans 9 years after baseline.
Accuracy and variability in clinical predictions of speech recognition outcomes for cochlear implant users.
Int J Audiol
January 2025
Department of Otolaryngology, Vanderbilt University Medical Center, Nashville, TN, USA.
Objectives: An improvement in speech perception is a major well-documented benefit of cochlear implantation (CI), which is commonly discussed with CI candidates to set expectations. However, a large variability exists in speech perception outcomes. We evaluated the accuracy of clinical predictions of post-CI speech perception scores.
View Article and Find Full Text PDFXIS-PM: A daily spatiotemporal machine-learning model for PM in the contiguous United States.
Environ Res
January 2025
Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA; The Department of Geography and Environmental Development, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Air-pollution monitoring is sparse across most of the United States, so geostatistical models are important for reconstructing concentrations of fine particulate air pollution (PM) for use in health studies. We present XGBoost-IDW Synthesis (XIS), a daily high-resolution PM machine-learning model covering the contiguous US from 2003 through 2023. XIS uses aerosol optical depth from satellites and a parsimonious set of additional predictors to make predictions at arbitrary points, capturing near-roadway gradients and allowing the estimation of address-level exposures.
View Article and Find Full Text PDFLinear and angular impulse generated by high school pitchers during fastballs and changeups.
J Biomech
January 2025
Stevens Institute of Technology, Hoboken, NJ, USA. Electronic address:
This study revealed how high school pitchers generated momenta during fastballs and changeups at a whole-body level. Baseball pitchers control ground reaction forces to generate whole-body momentum. Pitchers attempt to throw as fast and accurately as possible during fastballs but also need to throw off-speed pitches like changeups to deceive batters.
View Article and Find Full Text PDFARCH: Large-scale knowledge graph via aggregated narrative codified health records analysis.
J Biomed Inform
January 2025
Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, 02115, MA, USA; VA Boston Healthcare System, 150 S Huntington Ave, Boston, 02130, MA, USA. Electronic address:
Objective: Electronic health record (EHR) systems contain a wealth of clinical data stored as both codified data and free-text narrative notes (NLP). The complexity of EHR presents challenges in feature representation, information extraction, and uncertainty quantification. To address these challenges, we proposed an efficient Aggregated naRrative Codified Health (ARCH) records analysis to generate a large-scale knowledge graph (KG) for a comprehensive set of EHR codified and narrative features.
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