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Assessing the accuracy and usefulness of YouTube videos on small incision lenticule extraction (SMILE) surgery for patients and healthcare professionals.
Lasers Med Sci
January 2025
Department of Ophthalmology, University of Health Sciences, Beyoglu Eye Training and Research Hospital, Istanbul, 34420, Turkey.
To evaluate the quality, usefulness, and reliability of videos about Small Incision Lenticule Extraction (SMILE) surgery on the YouTube platform. On January 19, 2022, a search was performed on YouTube ( www.youtube.
View Article and Find Full Text PDFUncovering Psychedelics: From Neural Circuits to Therapeutic Applications.
Pharmaceuticals (Basel)
January 2025
Department of Translational Research and New Surgical and Medical Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
Psychedelics, historically celebrated for their cultural and spiritual significance, have emerged as potential breakthrough therapeutic agents due to their profound effects on consciousness, emotional processing, mood, and neural plasticity. This review explores the mechanisms underlying psychedelics' effects, focusing on their ability to modulate brain connectivity and neural circuit activity, including the default mode network (DMN), cortico-striatal thalamo-cortical (CSTC) loops, and the relaxed beliefs under psychedelics (REBUS) model. Advanced neuroimaging techniques reveal psychedelics' capacity to enhance functional connectivity between sensory cerebral areas while reducing the connections between associative brain areas, decreasing the rigidity and rendering the brain more plastic and susceptible to external changings, offering insights into their therapeutic outcome.
View Article and Find Full Text PDFArgonaute2 and Argonaute4 Involved in the Pathogenesis of Kawasaki Disease via mRNA Expression Profiles.
Children (Basel)
January 2025
Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.
Background: Argonautes (AGOs) are a type of protein that degrade specific messenger RNAs, consequently reducing the expression of a specific gene. These proteins consist of small, single-stranded RNA or DNA and may provide a route for detecting and silencing complementary mobile genetic elements. In this research, we investigated which AGO(s) were involved in Kawasaki disease (KD).
View Article and Find Full Text PDFComparative analysis of certified emission reduction methodologies for methane emission reduction in China.
J Environ Manage
January 2025
School of Environment and Safety Engineering, Qingdao University of Science Technology, Qingdao, 266042, China.
As one of the top emitters of methane (CH), China must take action to achieve its carbon neutrality goal. Programs to reduce CH emissions would benefit from the establishment of the China Certified Emission Reduction (CCER) trading market. However, studies investigating the impact of the CCER trading market on CH reduction remain limited.
View Article and Find Full Text PDFTuberculosis treatment outcomes and associated factors among patients treated at Bosaso TB Hospital, Bosaso, Somalia: A five-year retrospective study.
PLoS One
January 2025
Administration Department, Ministry of Health (Puntland), Bosaso, Puntland, Somalia.
Introduction: Tuberculosis remains a major public health problem, primarily in low- and middle-income countries. Evaluating treatment outcomes and investigating factors associated with them are essential for the treatment and control of tuberculosis. Hence, this study aims to assess the TB treatment outcomes and associated factors in Bosaso, Puntland, Somalia.
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