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Introduction: Children and adolescents with neurodevelopmental and psychiatric comorbidities, particularly autism spectrum disorder and developmental delays (ASD/DD), present unique challenges in pediatric emergency department (PED) settings. Youths with ASD/DD are prone to sensory overload and frequently exhibit agitation and/or aggression, necessitating specialized interventions. However, PEDs lack standardized protocols for managing behavioral dysregulation in this vulnerable population, often relying on anecdotal treatment approaches that hinder the provision of safe, effective and individualized care.
View Article and Find Full Text PDFA Narrative Review on the Neurocognitive Profiles in Eating Disorders and Higher Weight Individuals: Insights for Targeted Interventions.
Nutrients
December 2024
Orygen, Parkville, VIC 3052, Australia.
: Recent research has increasingly explored the cognitive processes underlying eating disorders (EDs), including anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), other specified feeding or eating disorders (OSFEDs), and individuals with higher weight (HW). This critical narrative review focuses on neurocognitive findings derived from mainly experimental tasks to provide a detailed understanding of cognitive functioning across these groups. Where experimental data are lacking, we draw on self-report measures and neuroimaging findings to offer supplementary insights.
View Article and Find Full Text PDFWhite Coats at a Crossroads: Hygiene, Infection Risk, and Patient Trust in Healthcare Attire-An Umbrella Review with Quantitative Synthesis and Stress, Weaknesses, Opportunities, and Threats Analysis.
Microorganisms
December 2024
Pediatric Orthopedic and Trauma Surgery, Children's University Hospital Zürich, 8008 Zürich, Switzerland.
White coats, traditionally symbols of physicians' hygiene and professionalism, are now scrutinized for potential infection risks during patient interactions. This review investigates whether wearing white coats is linked to microbial contamination, infection transmission, and patient expectations. An umbrella review of peer-reviewed studies and guidelines was conducted, with searches in PubMed/Medline and Scopus using terms related to medical attire, infection control, patient perceptions, and discrimination.
View Article and Find Full Text PDFDrug Safety During Breastfeeding: A Comparative Analysis of FDA Adverse Event Reports and LactMed.
Pharmaceuticals (Basel)
December 2024
Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium.
Background/objectives: While breastfeeding is highly recommended, breastfed infants may be exposed to drugs by milk due to maternal pharmacotherapy, resulting in a risk of adverse drug events (ADE) or reactions (ADRs). The U.S.
View Article and Find Full Text PDFPandemic-Proofing: Intercepting Zoonotic Spillover Events.
Pathogens
December 2024
Molecular and Translational Virology, Centre for Virus Research, Vaccines and Therapeutics, Translational Health Science and Technology Institute, NCR Biotech Science Cluster, Faridabad 121001, India.
Zoonotic spillover events pose a significant and growing threat to global health. By focusing on preventing these cross-species transmissions, we can significantly mitigate pandemic risks. This review aims to analyze the mechanisms of zoonotic spillover events, identify key risk factors, and propose evidence-based prevention strategies to reduce future pandemic threats.
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