Increased pressor response to the infusion of alpha1-adrenoceptor agonist phenylephrine was observed in conditions of inhibited NO synthesis: the mean blood pressure increased from 33.7 to 41.1% and the total peripheral resistance increased from 6.8 to 22.0%. The effect of vasodilation induced by NO secretion in the vascular endothelium after the stimulation by alpha1-adrenoceptors on the degree of pressor changes and changes in the total peripheral resistance is proposed.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
total peripheral
8
peripheral resistance
8
[involvement nitric
4
nitric oxide
4
oxide mechanism
4
mechanism adrenergic
4
adrenergic responses
4
responses systemic
4
systemic circulation]
4
circulation] increased
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!