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Effects of Chiral Polypeptides on Skyrmion Stability and Dynamics.
Nano Lett
December 2024
Institute of Applied Physics, Faculty of Sciences, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.
Magnetic skyrmions, topologically stabilized chiral spin textures in magnetic thin films, have garnered considerable interest due to their efficient manipulation and resulting potential as efficient nanoscale information carriers. One intriguing approach to address the challenge of tuning skyrmion properties involves using chiral molecules. Chiral molecules can locally manipulate magnetic properties by inducing magnetization through spin exchange interactions and by creating spin currents.
View Article and Find Full Text PDFGenetic Tools in Rodents to Study Cannabinoid Functions.
Curr Top Behav Neurosci
December 2024
Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
During the past 30 years, the endocannabinoid system (ECS) has emerged as a major signalling system in the mammalian brain regulating neurotransmission in numerous brain regions and in various cell populations. Endocannabinoids are able to regulate specific physiological functions and thus modify their behavioural manifestations and allostatic alterations of the ECS linked to different pathological conditions. As discussed in detail in other chapters of this book, endocannabinoids are involved in learning and memory, stress, and anxiety, feeding, energy balance, development, and ageing.
View Article and Find Full Text PDFDifferential predictive value of resident memory CD8T cell subpopulations in patients with non-small-cell lung cancer treated by immunotherapy.
J Immunother Cancer
December 2024
Université Paris Cité, INSERM, PARCC, Paris, France, Paris, France
Background: A high density of resident memory T cells (T) in tumors correlates with improved clinical outcomes in immunotherapy-treated patients. In most clinical studies, T are defined by the CD103 marker. However, it is clearly established that not all T express CD103, but can be defined by other markers (CD49a, CD69, etc).
View Article and Find Full Text PDFTransient impact of chronic social stress on effort-based reward motivation in non-food restricted mice: Involvement of corticosterone.
Neurobiol Stress
November 2024
Leibniz Institute for Resilience Research (LIR), Mainz, Germany.
Chronic stress has been connected to a reduced effort and motivational deficits. To study effort-based motivation in rodents, operant conditioning is often employed. However, caloric restriction is typically imposed simultaneously.
View Article and Find Full Text PDFTowards integrating imaging and immunology in glioblastoma: mapping blood immune system metrics to tumor magnetic resonance image data.
Acta Neuropathol Commun
November 2024
Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Background: Glioblastoma is the most frequent and aggressive brain cancer. It is a highly immunology-driven disease as up to a third of its mass is composed of immune cells. Apart from immunology, imaging is a major research frontier.
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