Objective: To review the treatment of repair gastroschisis with autogenous umbilical cord in 13-year and evaluate its effect.
Methods: Twenty-two newborns who underwent the repair gastroschisis with autogenous umbilical cord between 1992 and 2005. The physical growth, intelligence measuring, area of operation in abdomen in the survived 18 cases were observed and followed-up.
Results: Eighteen patients recovered uneventfully, survival rate is 82%, their growth is well. They all developed incisional hernia near the operation, 9 cases recovered himself, 2 cases was operated to repair the abdominal hernia, 7 cases is under observed.
Conclusions: The material is adopted easily in the operating, autogenous umbilical cord is elastic tissue and no toxicity could relax the abdominal press effectively after the operation, the survival rate is high.
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Article Synopsis
- The study explores the use of human umbilical cord mesenchymal stem cells (h-UCMSCs) as an alternative graft material for alveolar cleft repair (ACR), comparing it with traditional methods using PLGA scaffolds.
- In a controlled mouse model, the researchers created bone defects and analyzed the effects of various treatments on bone regeneration over 4 weeks.
- Results showed that h-UCMSCs combined with PLGA significantly improved bone fill compared to no treatment or PLGA alone, suggesting potential for future clinical applications in bone repair.
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