AI Article Synopsis
- The study examines the relationship between assisted reproductive technology (ART) and negative outcomes for mothers and infants, focusing on singleton births.
- Data from the US ART surveillance and Massachusetts birth records (1997-1998) were analyzed, revealing that ART is linked to higher risks of various complications.
- Despite controlling for various factors, ART conception still showed increased risks for conditions like diabetes, hypertension, preterm delivery, and low birth weight in mothers and infants.
Article Abstract
Objective: To assess associations between assisted reproductive technology (ART) and adverse maternal and infant outcomes, with an emphasis on singletons.
Methods: We linked data from the US ART surveillance system with Massachusetts live birth-infant death records data for resident births in 1997-1998 and compared births conceived with ART (N = 3316) with births not conceived with ART or infertility medications (N = 157,066) on: maternal chronic conditions, pregnancy complications, labor and delivery complications, and perinatal and infant outcomes.
Results: Overall, ART was strongly associated with numerous adverse outcomes. The magnitude was reduced for several outcomes when analyses were limited to singletons. After further exclusion of maternal subsets with rare ART births (maternal age <20; education
Conclusions: Women who conceive with ART are more likely than women who do not to enter pregnancy with a chronic condition and develop complications during pregnancy and labor and delivery. Additionally, infants born after ART are at increased risk for adverse health outcomes. The mechanisms underlying these associations require further study.
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| http://dx.doi.org/10.1007/s10995-007-0202-7 | DOI Listing |
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