Successful pregnancy outcome with the use of in vitro fertilization after Essure hysteroscopic sterilization.

Objective: To assess the compatibility of pregnancy after IVF and ET procedures with the presence of the Essure microinsert.

Design: Prospective, single-arm, clinical study (Canadian Task Force classification III).

Setting: Clinical research center.

Patient(s): Two women requesting IVF and ET procedures after Essure microinsert sterilization.

Intervention(s): Hysteroscopic sterilization, followed by IVF and ET procedures.

Main Outcome Measure(s): Successful implantation and pregnancy outcomes after IVF procedures.

Result(s): Both patients underwent a second-look hysteroscopy within 3 months of an IVF procedure. Device encapsulation by tissue ingrowth reduced the average number of coils trailing into the uterine cavity from four to one, with no evidence of inflammation or any other abnormality. One woman conceived in her second IVF cycle after the transfer of two embryos, and the second woman conceived in her first cycle after the transfer of 1 embryo. Ultrasound showed that the proximal echogenic segments of the microinserts remained > or =10 mm distant from the pregnancy sac. Both women had spontaneous vaginal deliveries of healthy female infants. Postpartum ultrasound demonstrated that the microinserts maintained their prepregnancy utero-tubal locations.

Conclusion(s): The Essure microinsert used for hysteroscopic sterilization may be compatible with implantation and successful pregnancy outcomes after IVF.