In a skin irritancy study in healthy volunteers with 3 metal salts, aqueous gold sodium thiosulfate (GSTS) in a dilution series caused unexpectedly frequent and strong patch test reactions on volar forearm skin in 22 of 31 participants (71%). The reactions showed morphological features consistent with a contact allergic reaction, and the crescendo type of the response speaks in favour of an allergic nature. Further, 8 of the 31 (26%) developed long-lasting test reactions. A follow-up interview among 28/31 participants 10 years later showed that none had experienced long-term consequences in the form of skin and/or mucosal complaints related to exposure to gold items. The results indicate that inclusion of GSTS in routine patch testing may cause problems regarding interpretation and clinical relevance of positive GSTS patch tests, which fulfil the clinical criteria of a contact allergy.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1600-0536.2007.01049.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Sodium fluorescein video Angiography-Assisted clipping of intracranial Aneurysms: A systematic review and Meta-Analysis.
J Clin Neurosci
January 2025
Department of Neurosurgery, Lenox Hill Hospital/Northwell Health, New York, NY, USA.
Objectives: Ensuring aneurysm exclusion while maintaining vessel patency is crucial during intracranial aneurysm clipping. Although digital subtraction angiography (DSA) is the gold standard for intraoperative vascular imaging, some centers have reported using fluorescein sodium video angiography (FNa-VA). However, a synthesis of these findings is still lacking.
View Article and Find Full Text PDFChanges of b2-microglobulin and electrolytes in different stages of COPD and their value in evaluating prognosis.
J Med Biochem
November 2024
Central South University, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Department 2 of Respiratory and Critical Medicine, Zhuzhou, China.
Background: To investigate the changes of b2-microglobulin and electrolyte in different stages of chronic obstructive pulmonary disease (COPD) and the value of evaluating prognosis.
Methods: A retrospective study was undertaken on 120 patients diagnosed with COPD and treated at our respiratory department between February 1, 2020, and January 31, 2023. These patients were classified into three groups based on the GOLD classification: mild (FEV1 > 81%), moderate (51% < FEV1 ≤ 80%), and severe (FEV1 ≤ 50%).
Polymeric hydrogel integrated paper-based potentiometric ion-sensing device for the determination of sodium ions in human urine.
Analyst
January 2025
Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan.
A paper-based potentiometric sensor integrated with a polymeric hydrogel has been developed for sodium ion (Na) determination in human urine. The construction of an all-solid-state ion selective electrode (s-ISE) and an all-solid-state reference electrode (s-RE) on a photo paper substrate was achieved using an inkjet printing method. For s-ISE fabrication, carbon nanotubes (CNTs) and gold nanoparticles (AuNPs) were printed on the substrate as a nanocomposite solid contact.
View Article and Find Full Text PDFPropolis mouthwashes efficacy in managing gingivitis and periodontitis: a systematic review of the latest findings.
BDJ Open
January 2025
Department of Orthodontics, Institute of Dentistry, Medical Faculty, Jagiellonian University, Kraków, Poland.
Background And Objectives: Gingivitis and periodontitis are common periodontal diseases that can significantly harm overall oral health, affecting the teeth and their supporting tissues, along with the surrounding anatomical structures, and if left untreated, leading to the total destruction of the alveolar bone and the connective tissues, tooth loss, and other more serious systemic health issues. Numerous studies have shown that propolis can help reduce gum inflammation, inhibit the growth of pathogenic bacteria, and promote tissue regeneration, but with varying degrees of success reported. For this reason, this comprehensive systematic review aims at finding out the truth concerning the efficacy of propolis mouthwashes in treating gingivitis and periodontitis, as its main objective.
View Article and Find Full Text PDFAn Ultra-Wide Range D-Shaped Fiber SPR Sensor with a Nanostructure of Gold-MoS and Sodium for the Simultaneous Measurement of Refractive Index and Temperature.
Sensors (Basel)
January 2025
School of Physics and Electronic Engineering, Guangzhou University, Guangzhou 510006, China.
Refractive index (RI) and temperature (T) are both critical environmental parameters for environmental monitoring, food production, and medical testing. The paper develops a D-shaped photonic crystal fiber (PCF) sensor to measure RI and T simultaneously. Its cross-sectional structure encompasses a hexagonal-hole lattice, with one hole selectively filled with toluene for temperature sensing.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!