Objective: The Authors report their experience in diagnosis and treatment of one case of mesenteric cystic lymphangioma; recent international literature review.

Experimental Design: Complete clinical report. Diagnostic, clinical and prognostic indication, evaluation of effectiveness of radical surgical treatment and follow-up.

Setting: Operative Unit of General and Thoracic Surgery. University "Paolo Giaccone" of Palermo.

Intervention: Radical surgical treatment, according to international guide-lines.

Results: Complete recovery with "restitutio ad integrum". No relapse were recorded at short follow up.

Conclusions: Even when asymptomatic and discovered incidentally, LCM must be treated surgically because of the potential to grow, invade vital structures, and develop life-threatening complications. The best and only radical treatment is the total removal of the lesions with microscopically clear borders, when it is available.

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