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Clinical Manifestations.
Alzheimers Dement
December 2024
Fleni, Buenos Aires, Buenos Aires, Argentina.
Background: Surface dyslexia serves as a complementary feature in the classification of the semantic variant of Primary Progressive Aphasia (PPA), while reading deficits have also been reported in the other two PPA variants. In opaque languages, tasks involving regular and irregular words and non-words are useful tools for dyslexia diagnosis. However, in transparent languages like Spanish, where most words are regular for reading, different approaches are needed.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Sorbonne Université, Paris Brain Institute - Institut du Cerveau - ICM, Inserm U1127, CNRS UMR 7225, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France.
Background: Anosognosia, a hallmark of Alzheimer's disease (AD), manifests as a gradual decline in disease awareness, yet its neural correlates remain unclear. This study investigates how amyloid accumulation, glucose hypometabolism and cortical atrophy relate to cognitive awareness across the AD continuum. Both the pathological processes and the brain regions involved were studied.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea, Republic of (South).
Background: Numerous studies have demonstrated an association between altered liver function and Alzheimer's disease (AD) or related dementia. Nevertheless, the neuropathological substrates underlying the association remains unclear. Our aim was to investigate the association between liver function markers and the longitudinal changes of in vivo AD pathologies.
View Article and Find Full Text PDFPrognostic value of [F]FDG PET/CT in patients with idiopathic pulmonary fibrosis.
Sci Rep
January 2025
Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
The study investigates the prognostic value of [F]fluorodeoxyglucose (FDG) PET/CT in patients with idiopathic pulmonary fibrosis (IPF). A total of 346 IPF patients who underwent FDG PET/CT between 2007 and 2020 were analyzed. Pulmonary FDG uptake [target to background ratio (TBR)] was binarized by optimal cut-off value based on survival analysis.
View Article and Find Full Text PDFUtility of FDG PET/CT in Sjögren's Syndrome and associated lymphomas; Lymphomagenesis.
Asia Ocean J Nucl Med Biol
January 2025
Department of Nuclear Medicine, Institute of Liver and Biliary Sciences, New Delhi, Delhi, India.
Primary Sjögren syndrome (SS) is an autoimmune disease affecting exocrine glands, with predisposition to development of lymphoma (lymphomagenesis). We report a case of Sjogren's syndrome and discuss the role of FDG PET/CT in the primary diagnosis of lymphoma transformation in SS. Furthermore, we reviewed the literature regarding the utility of FDG PET/CT to assess systemic disease activity and also its role in the SS associated lymphoma with light into the new PET tracers that can be explored for these indications in the future.
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