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Serum amyloid A levels are increased in pre-eclampsia. | LitMetric

Serum amyloid A levels are increased in pre-eclampsia.

Gynecol Obstet Invest

Department of Obstetrics and Gynecology, School of Medicine, Inonu University, Malatya, Turkey.

Published: October 2007

AI Article Synopsis

Article Abstract

Aim: The purpose of this study was to examine serum amyloid A (SAA) levels in normal pregnant and pre-eclamptic women.

Methods: SAA levels were measured in 25 normotensive and 25 pre-eclamptic pregnant women by enzyme linked immuno-sorbent assay.

Results: In pre-eclampsia, SAA level and C-reactive protein (CRP) averaged 28.2 (7.2-135) ng/l and 21 (6.13-91) mg/l, respectively, which were significantly higher than those of normal pregnancy (7.8 [4.65-24.6] ng/l and 6.05 [0.3-19] mg/l, respectively) (p < 0.05). In addition, SAA level was positively correlated to CRP (r = 0.468, p < 0.05).

Conclusion: Marked increases of both SAA level and CRP in pre-eclampsia, and their inter-relation, may at least in part contribute to the pathogenesis of pre-eclampsia.

Download full-text PDF

Source
http://dx.doi.org/10.1159/000100329DOI Listing

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