A new technique is described which measures the extent and time course of intracochlear bone formation after cochlear implantation in an experimental animal model. A series of fluorescent histochemical markers is used to delineate the amount of intracochlear bone deposition during specified time periods.
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http://dx.doi.org/10.1016/0378-5955(92)90157-i | DOI Listing |
Hear Res
January 2025
CHU Lille, Department of Otology and Neurotology, F-59000 Lille, France; Univ. Lille, France; Univ. Lille, Inserm, CHU Lille, U1008, F-59000 Lille, France.
Objective: The aim of this study is to detail and evaluate the surgical procedure for perilymph sampling from the cochlear apex in the Mongolian gerbil.
Design: Perilymph sampling from the cochlear apex was performed one to three time in 12 male gerbils aged 8 to 12 months via the submandibular route. 11 of them were previously implanted with intracochlear implants loaded with dexamethasone and placed in the scala tympani, the 12th was used to collect control samples.
J Acoust Soc Am
January 2025
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
The otic capsule and surrounding temporal bone exhibit complex 3D motion influenced by frequency and location of the bone conduction stimulus. The resultant correlation with the intracochlear pressure is not sufficiently understood, thus is the focus of this study, both experimentally and numerically. Experiments were conducted on six temporal bones from three cadaver heads, with BC hearing aid stimulation applied at the mastoid and classical BAHA locations across 0.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Neurosciences, Research Group Experimental Oto-rhino-laryngology, KU Leuven, Leuven, B3000, Belgium.
Bone conduction implants enable patients to hear via vibrations transmitted to the skull. The main constraint of current bone conduction implants is their maximum output force level. Stimulating closer to the cochlea is hypothesized to increase efficiency and improve force transfer, addressing this limitation.
View Article and Find Full Text PDFOtol Neurotol
February 2025
Department of Head and Neck Surgery, University of California Los Angeles, Los Angeles, California, U.S.A.
Hypothesis: The objective of this study is to obtain comprehensive morphometric measurements of the incomplete partition type II (IP-II) cochlea to provide a better understanding of intracochlear anatomy and important considerations for electrode selection and insertion.
Background: IP-II is the most common bony inner ear malformation that often requires cochlear implantation. Currently, there is significant controversy on electrode selection due to a lack of research that can provide reliable, high-resolution measurements.
Eur Arch Otorhinolaryngol
November 2024
ENT Institute and Department of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 20031, China.
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