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cutaneous melanoma has often unpredictable lymphatic drainage patterns, especially at the level of the trunk, head and neck regions. Sentinel lymph node biopsy (SLNB) is an important prognostic tool that accurately assesses regional lymph node involvement and guides therapeutic decisions. Material and this prospective study involved 104 patients diagnosed with cutaneous melanoma who underwent SLNB using a radioactive tracer.
View Article and Find Full Text PDFClinical implication of metastasis in the second most radioactive sentinel lymph node with nonmetastatic most radioactive node in patients with breast cancer.
Gland Surg
November 2024
Division of Breast and Endocrine Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Background: Sentinel lymph node biopsy (SNB) using radioisotopes is a standard method for assessing axillary lymph node status in patients with breast cancer. Although preoperative lymphoscintigraphy can estimate the number of sentinel lymph nodes (SNs), multiple radioactive SNs are often identified, even when lymphoscintigraphy reveals only one SN. Importantly, metastases are not always observed in the most radioactive SN (hottest SN).
View Article and Find Full Text PDFSentinel lymph node mapping with Indocyanine green fluorescence (ICG) for pediatric and adolescent tumors: a prospective observational study.
Sci Rep
December 2024
Department of Surgery, MS133, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105-3678, USA.
Sentinel lymph node biopsy (SLNB) is an important technique in the staging of pediatric melanomas, sarcomas, and potentially useful for other solid tumors. Precise visual localization of the sentinel lymph node (SLN) during the operation is a key challenge of this procedure. Presently, the gold standard method employing Technetium 99 (99mTc) for localization carries a notable false-negative rate.
View Article and Find Full Text PDFArticle Synopsis
- * Tests showed that a radionuclide was leaking into her abdominal cavity, indicating a problem with her lymphatic vessels.
- * Treatment with lymphangiography using Lipiodol successfully resolved the chylous ascites, suggesting this method can diagnose and treat lymphatic vessel injuries in similar cases.
Comparison of Indocyanine Green with conventional tracers for sentinel lymph node biopsy in breast cancer: A multidisciplinary evaluation of clinical effectiveness, safety, organizational and economic impact.
PLoS One
August 2024
Oncology Department Azienda Ospedaliera Universitaria Integrata (AOUI) Verona, Complex Operative Unit (UOC) Breast Surgery, Breast Unit, Verona, Italy.
Background: Breast cancer is a global health problem, and sentinel lymph node biopsy (SLNB) is the standard procedure for early-stage breast cancer. Technetium-99 (TC-99), alone or combined with blue dye (BD) are conventional tracers for SLNB, but they have safety, availability, and cost limitations. Indocyanine green (ICG) is an alternative tracer that has been gaining acceptance among healthcare professionals.
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