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A sellar presentation of a WNT-activated embryonal tumor: further evidence of an ectopic medulloblastoma.
Acta Neuropathol Commun
April 2023
Department of Neuropathology, GHU Paris-Psychiatrie et Neurosciences, Sainte-Anne Hospital, 1, Rue Cabanis, 75014, Paris, France.
Surgical Treatment for Recurrent Dupuytren Disease.
Hand (N Y)
June 2023
INTEGRIS Health, Oklahoma City, OK, USA.
Background: Revision procedures for recurrent Dupuytren disease (DD) can be difficult and carry a high risk of complications. Our goal was to describe surgical strategies used for cases of recurrence and report on their outcomes.
Methods: We reviewed 1 surgeon's operative cases for recurrent DD performed at 1 institution.
Skin grafting prevents recurrence in Dupuytren's disease and extension correlates with fibrosis diathesis score.
Hand Surg Rehabil
September 2021
Department of Orthopedic Surgery, UZ Leuven, Herestraat 49, Leuven, Belgium.
Full thickness grafting can be considered after fasciectomy for Dupuytren contracture in severe cases with skin shortage or in radical dermofasciectomy. It is a common dogma that these skin grafts may prevent disease recurrence. We reviewed 47 patients after fasciectomy and full-thickness skin grafting for Dupuytren contracture at 3-16 years' follow-up.
View Article and Find Full Text PDFLimited progression of subclinical Dupuytren's disease.
Bone Joint J
April 2021
Department of Plastic Surgery, University Medical Center Groningen, Groningen, the Netherlands.
Aims: With novel promising therapies potentially limiting progression of Dupuytren's disease (DD), better patient stratification is needed. We aimed to quantify DD development and progression after seven years in a population-based cohort, and to identify factors predictive of disease development or progression.
Methods: All surviving participants from our previous prevalence study were invited to participate in the current prospective cohort study.
A Weighted Genetic Risk Score Predicts Surgical Recurrence Independent of High-Risk Clinical Features in Dupuytren's Disease.
Plast Reconstr Surg
February 2019
From the Departments of Plastic Surgery and Epidemiology, University of Groningen, University Medical Center Groningen; and the Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford University.
Background: Dupuytren's disease is a very common, highly heritable palmar fibromatosis. In a recent genome-wide association study, 26 single-nucleotide polymorphisms were found to be associated with development of Dupuytren's disease. The authors generated a weighted genetic risk score based on the genotype at these single-nucleotide polymorphisms.
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