AI Article Synopsis
- Bone and joint infections from Aspergillus, particularly Aspergillus fumigatus, are uncommon but more likely in immunosuppressed individuals.
- An 84-year-old woman experienced septic arthritis in her left knee following multiple corticosteroid injections, with no prior diagnosis of microorganisms until an arthroscopy revealed A. fumigatus.
- Despite aggressive treatment including voriconazole and surgical intervention, the patient ultimately passed away, highlighting the severe complications that can arise from such infections, especially following corticosteroid use.
Article Abstract
Bone and joint infections due to Aspergillus are rare and occur more commonly in immunosuppressed patients. We report the case of an 84-year-old woman who developed septic arthritis caused by Aspergillus fumigatus after corticosteroid infiltration. This patient had presented with arthritis of the left knee for several months but no microorganism had been found despite numerous arthrocenteses. This arthritis was resistant to treatment by numerous corticosteroid infiltrations. During an arthroscopy, analysis of the synovial fluid yielded A. fumigatus. Thereafter, other explorations showed disseminated aspergillosis with osteo-articular destruction, blood and urinary dissemination. A systemic treatment by voriconazole associated to intra-articular injections and surgical debridement was initiated but the patient died. Septic arthritis caused by A. fumigatus is very rare but must be considered as a differential diagnosis of septic arthritis after corticosteroid infiltration. Their complications can be very important and destructive.
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| http://dx.doi.org/10.1016/j.medmal.2006.12.008 | DOI Listing |
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