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Physiologic Pulmonary Phenotyping of Infants Born Preterm and Post-Discharge Respiratory Morbidity.
J Pediatr
January 2025
Section of Pediatric Pulmonary Medicine and the Pediatric Heart Lung Center, Department of Pediatrics, University of Colorado Anschutz School of Medicine.
Objectives: To determine whether airway and parenchymal function identifies subgroups of infants born preterm according to the predominant pulmonary pathophysiology, and whether these subgroups have different risks for respiratory disease during infancy.
Study Design: We prospectively enrolled a cohort of 125 infants born preterm with planned clinical follow-up after NICU discharge. The study included monthly questionnaires for wheeze and visits to a physician or care provider for any respiratory illness.
Indoor air quality and human health risk assessment in selected high-altitude villages of Gilgit-Baltistan, Pakistan.
Environ Monit Assess
January 2025
Department of Environmental Sciences, Karakoram International University, Gilgit, Gilgit-Baltistan, Pakistan.
This research marks the inaugural endeavor in Gilgit-Baltistan (GB) to identify the primary sources of household energy and indoor air pollutants (IAPs) during the winter and additionally, to evaluate the health impacts associated with IAPs within specific high-altitude communities in Gilgit-Baltistan, Pakistan. Using the convenience sampling method, 20 households were continuously monitored to assess IAPs based on standards time-weighted average. The study found that 90% of the population relied primarily on animal dung as their main energy source, with wood, agricultural residues, electricity, and gas as other sources.
View Article and Find Full Text PDFEffect of relaxing sounds on anxiety levels in patients undergoing dental extraction: A randomized clinical trial.
Natl J Maxillofac Surg
November 2024
Department of Oral and Maxillofacial Surgery and Diagnostic Science, College of Dentistry, Prince Sattam Bin Abdullaziz University, Riyadh, Saudi Arabia.
Introduction: The study was conducted to observe the effect of using relaxing sounds as a nonpharmacological intervention on anxiety levels and vital signs among patients who underwent extraction.
Materials And Methods: A randomized clinical trial was conducted, and patients with an indication of dental extraction, who were physically and mentally healthy, were invited to voluntarily participate in the study. Dental anxiety was assessed by measuring blood pressure, heart rates, and respiratory rates as well as with the help of the Modified Dental Anxiety Scale (MDAS) questionnaire before and after the procedure.
Automated system for diagnosing pulmonary fibrosis using crackle analysis in recorded lung sounds based on iterative envelope mean fractal dimension filter.
Physiol Meas
January 2025
Universita Cattolica del Sacro Cuore, Rome, Italy, Largo Francesco Vito, 1, 00168 Roma RM, Italy, Rome, 00168, ITALY.
Patients with pulmonary fibrosis (PF) often experience long waits before getting a correct diagnosis, and this delay in reaching specialized care is associated with increased mortality, regardless of the severity of the disease. Early diagnosis and timely treatment of PF can potentially extend life expectancy and maintain a better quality of life. Crackles present in the recorded lung sounds may be crucial for the early diagnosis of PF.
View Article and Find Full Text PDFConsensus outcomes between health professionals and parents for oral corticosteroids in treating preschool wheeze: a multi-national survey and nominal group technique study.
Arch Dis Child
January 2025
Department of Child Life and Health, University of Edinburgh Institute for Regeneration and Repair, Edinburgh, UK.
Objective: To obtain priority consensus for outcome measures of oral corticosteroid treatment of preschool wheeze that represent stakeholder groups.
Design: (1) A systematic review to identify a set of outcome measures; (2) an international survey for healthcare professionals (HCPs) and a nominal group meeting with parents; (3) a final consensus nominal group meeting with key HCPs (trial investigators and paediatric emergency medicine clinicians) and the same parent group.
Main Outcome Measures: Consensus priority of treatment outcome measures, outcome minimal clinically important differences (MCIDs) and level of concerns about adverse effects.
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