A 22-year-old woman presented with pain on the dorsum of her left big toe. The patient had had an accident 1 year previously, when a heavy object fell on her left big toe. She experienced no pain in the hallux before the injury. Radiographic evaluation revealed a well-circumscribed osseous mass, in close relationship to the underlying dorsal cortex of the proximal phalanx. A 2 x 1.5 x 0.7 cm mass was resected. No communication was found between the undersurface of the bony mass and the medullar space of the phalanx. The histology report confirmed diagnosis of acquired osteochondroma. Removal of the bony mass resulted in disappearance of symptoms without any sign of recurrence 10 months later.
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http://dx.doi.org/10.1053/j.jfas.2006.11.006 | DOI Listing |
Soc Stud Sci
January 2025
Science, Technology and Innovation Studies, The University of Edinburgh, Edinburgh, Scotland, UK.
Accounts of the origins of the genomic commons typically focus on the development of public repositories and data-sharing agreements. This article tells a different story. During the 1990s in the United States, efforts of private companies to prevent the patenting of certain kinds of DNA sequences were essentially a conservative response to shifts in the sociotechnical constitution of the pharmaceutical innovation system, and to the operation of intellectual property as one of the key knowledge control regimes that regulate that system.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
January 2025
Department of Growth and Development, Capital Institute of Pediatrics, Beijing, China.
Context: Bone age assessment (BAA) is critical for pediatric endocrinology. Traditional methods are complex and time-consuming, and current computer-aided systems have made progress but still lacking in robustness.
Objective: Develop simplified BAA methods to aid pediatricians in quick clinical assessments.
JACC Asia
December 2024
Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, and Chang Gung University College of Medicine, Taoyuan, Taiwan.
Background: Few studies have incorporated echocardiography and laboratory data to predict clinical outcomes in heart failure with preserved ejection fraction (HFpEF).
Objectives: This study aimed to use machine learning to find predictors of heart failure (HF) hospitalization and cardiovascular (CV) death in HFpEF.
Methods: From the Chang Gung Research Database in Taiwan, 6,092 HFpEF patients (2,898 derivation, 3,194 validation) identified between 2008 and 2017 were followed until 2019.
Cureus
January 2025
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, SAU.
Isolated foot drop is a neurological sign frequently linked to lower motor neuron (LMN) lesions, including peroneal nerve damage or L4-L5 radiculopathy. Nonetheless, upper motor neuron (UMN) lesions, such as strokes or tumors located in the parasagittal motor cortex, may sometimes manifest as isolated foot drops. The main causes of isolated foot drop secondary to central etiologies are uncommon, with few instances documented in the literature.
View Article and Find Full Text PDFJ Affect Disord
January 2025
Department of Radiology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, Shandong 264000, PR China; Shandong Provincial Key Medical and Health Laboratory of Intelligent Diagnosis and Treatment for Women's Diseases (Yantai Yuhuangding Hospital), Yantai, Shandong 264000, PR China; Big Data and Artificial Intelligence Laboratory, Yantai Yuhuangding Hospital, Qingdao University, Yantai, Shandong 264000, PR China. Electronic address:
Purpose: To elucidate the structural-functional connectivity (SC-FC) coupling in white matter (WM) tracts in patients with major depressive disorder (MDD).
Methods: A total of 178 individuals diagnosed with MDD and 173 healthy controls (HCs) were recruited for this study. The Euclidean distance was calculated to assess SC-FC coupling.
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