In this paper the problems that may arise when ivermectin is used in small animal medicine are discussed. A case-report is presented concerning a Canadian-American White Shepherd showing symptoms of fatal ivermectin poisoning following a normal dosage of ivermectin (220 micrograms per kilogramme of body weight). The treatment of dogs with ivermectin poisoning is described and some guide lines concerning the use of ivermectin are given.
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