The aim of this study was to assess the functional condition of thyroid remains after surgical treatment of mononodular goiter at different time points after operation. The trial has been conducted at Tbilisi N4 hospital. It was based on retrospective analysis of postoperative patients after mononodular goiter. 346 patients with mononodular euthyroid goiter were studied in order to learn the functional activity of thyroid gland in different time points after operation. From the first day after surgical interventions - hemythyroidectomy or subtotal resection one of the parts of thyroid (left or right), patients were getting replacement therapy with 25-50 mcg euthyrox. Monitoring of these patients have been conducted 1, 3, 6 months and 1, 3 and 5 years after operation. The clinical effect of treatment was assessed according to the following data: ultrasound grapy of the remain cult in thyroid gland and blood test data of thyroid hormones, such as FT4, TSH. Euthyrox in doses 50 mcg is recommended from the first day after operation, next the dose is corrected according to TSH data. It is necessary to control TSH level every six months in order to determine either to change the dose of euthyrox or its abrogation. It is recommended to keep TSH level between 0,5-2,0 M/U/L. Thyroid reminder will stabilize to the end of the year after operation. It is necessary a life control of patients after surgical treatment at least once a year (ultrasound of the remain cult of thyroid gland and TSH data.) to determine the condition of thyroid reminder.

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