Objective: To assess the value of prenatal diagnosis of placenta previa with placenta increta by transabdominal color Doppler ultrasound.
Methods: Two hundred and fourteen patients with persistent placenta previa underwent transabdominal color Doppler ultrasound for the prenatal diagnosis of placenta increta in our hospital from June 2002 to June 2005. We prospectively followed up their clinical and pathological results. The main color Doppler imaging criteria used included a loss of the normally visible retroplacental hypoechoic zone and/or a lacunar flow pattern showing marked or turbulent blood flow distributed within the subplacenta or intraparenchymal placenta area and extended into the surrounding tissues.
Results: (1) The sensitivity of color Doppler ultrasound in diagnosis of placenta previa increta was 77.3% (17/22) and the specificity was 98.4% (189/192). The positive and negative predictive values were 85.0% (17/20) and 97.4% (189/194) respectively. (2) The morbidity of placenta increta in women with placenta previa was 10.3% (22/214). The average amount of peripartum hemorrhage of placenta previa with increta (2494 ml) was higher than that of placenta previa without increta (505 ml). The morbidity of cesarean hysterectomy among women with placenta previa increta was 40.9% (9/22).
Conclusion: Placenta previa is a high-risk factor of placenta increta. Placenta previa increta threatens the lives of the mother and the fetus because of massive hemorrhage. Prenatal color Doppler ultrasound has a high sensitivity and specificity for the identification of placenta previa increta. It has a positive impact on the peripartum clinical management of the affected patients through reducing the death of the mother and the fetus because of unpredictive bleeding while terminating the pregnancy.
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Twin Res Hum Genet
January 2025
Necmettin Erbakan University Medical School of Meram, Department of Obstetrics and Gynecology, Division of Fetal and Maternal Medicine, Konya, Turkey.
This study aimed to create a risk prediction model with artificial intelligence (AI) to identify patients at higher risk of postpartum hemorrhage using perinatal characteristics that may be associated with later postpartum hemorrhage (PPH) in twin pregnancies that underwent cesarean section. The study was planned as a retrospective cohort study at University Hospital. All twin cesarean deliveries were categorized into two groups: those with and without PPH.
View Article and Find Full Text PDFInt J Gynaecol Obstet
January 2025
Department of Obstetrics and Gynecology, The First Affiliate Hospital of Jinan University, Jinan University, Guangzhou, China.
Objectives: To develop and validate a nomogram to predict severe postpartum hemorrhage following cesarean delivery.
Methods: This is a two-center retrospective cohort study. Cesarean delivery patients from the First Affiliate Hospital of Jinan University were divided into a development cohort (n = 11 137) and an internal validation cohort (n = 4739).
Biomaterials
January 2025
Translational Medicine Research Center, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China; Greater Bay Area Institute of Precision Medicine (Guangzhou), Fudan University, Guangzhou, 511462, China. Electronic address:
Cesarean section (CS) is highly prevalent surgery among females. However, current absorbable anti-adhesion membranes used clinically can partially prevent postoperative adhesions but show limited efficacy in tissue regeneration, leaving post-cesarean women at risk for severe complications including cesarean scar pregnancy, placenta previa, and uterine rupture. Herein, we designed a fully amniotic membrane (AM)-derived biomimetic nanostructural materials (AM-BNMs) as an anti-adhesion barrier, and validated its therapeutic efficacy in a rat CS model.
View Article and Find Full Text PDFCureus
December 2024
Obstetrics and Gynaecology, Centro Hospitalar de Leiria, Unidade Local de Saúde da Região de Leiria, Leiria, PRT.
Placenta accreta represents a spectrum of adherent placental anomalies and is an atypical invasion of the placenta. The major predisposing factor is a prior cesarean delivery. Placenta previa is considered an additional risk factor.
View Article and Find Full Text PDFCureus
December 2024
Obstetrics and Gynecology, Duhok Obstetrics and Gynecology Teaching Hospital, Duhok, IRQ.
Aims: To determine the effectiveness of tranexamic acid (TXA) in reducing vaginal bleeding, extending pregnancy duration, and enhancing perinatal outcomes in pregnant women with placenta previa.
Methods: A multicenter, randomized, double-blind clinical trial was conducted at three maternity teaching hospitals in Iraq's Kurdistan region, Azadi Hospital in the north of Iraq, and Al-Azhar University Hospital in Egypt on 146 women with placenta previa. Participants were randomly assigned to two interventional groups in a 1:1 ratio to receive either TXA or Dextrose 5% water (D5W).
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