This prospective study was carried out at a tertiary care hospital on 50 women with missed abortion up to 13 weeks who were given 600 mug misoprostol sublingually every 3 h for a maximum of three doses. Success rate was 86% (up to 72 h), and the acceptability of the method was 69.7%. Sublingual misoprostol is a non-invasive, effective and safe medical method for completion of abortion in missed abortion.
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http://dx.doi.org/10.1258/004947507779952023 | DOI Listing |
Sci Rep
January 2025
Department of Prenatal Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Early missed abortion is defined as a pregnancy of ≤ 12 weeks in which there is a cessation of life in the developing embryo or fetus, leading to its retention within the uterine cavity without being spontaneously expelled promptly. This condition is commonly observed and significantly impacts human reproductive health. This study aimed to identify key genes related to ferroptosis that could serve as novel biomarkers for early missed abortion.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
Department of Obstetrics and Gynecology, Affiliated Hospital of Southwest Jiaotong University, The Third People's Hospital of Chengdu, Chengdu, China.
Hysteroscopic procedures complicated by air embolism (AE) are exceptionally rare occurrences in clinical practice, and there have been no previously reported cases of AE associated with hysteroscopic dilation and curettage. While the overall incidence of this complication is low, the consequences can be devastating. During early pregnancy, the unique physiological changes, such as elevated hormonal levels and increased uterine blood supply, significantly heighten the risk of AE development.
View Article and Find Full Text PDFContraception
December 2024
Planned Parenthood South Atlantic, Raleigh, NC, USA and McLeod Regional Medical Center, Florence, SC, USA; University of Washington Department of Obstetrics and Gynecology, 1959 NE Pacific St, Box 356460, Seattle, WA 98005, USA; Pegasus Health Justice Center, Dallas, TX, 75207, USA; Washington University, St. Louis, MO, USA.
Early pregnancy loss (EPL), also known as miscarriage or spontaneous abortion, makes up 15-20% of all clinically recognized pregnancies. EPL is a broad term that includes intrauterine pregnancies (IUPs) with findings that suggest the pregnancy may not progress or definitely will not progress; pregnancies with a gestational sac (GS) in the lower endometrial cavity or endocervical canal in the process of expulsion; residual pregnancy tissue or persistent GS; and complete passage of the GS without residual tissue. This document addresses medication management of EPL in which the complete passage of the GS has not yet occurred, including pregnancies concerning for and diagnostic of EPL (sometimes called "missed abortion") and EPL in progress.
View Article and Find Full Text PDFAppl Ergon
December 2024
Human Factors and Complex Systems, School of Design and Creative Arts, Loughborough University, UK.
Ectopic pregnancies are uncommon among women presenting for abortion. However, where suspected, rapid referral for definitive diagnosis is essential to prevent harm. We assessed whether implementation of a standardised decision-making tool, an algorithmic representation of the clinical decisions and associated actions defined in policy, in a British abortion service was associated with a reduction in missed opportunities to escalate care where indicated.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
December 2024
Department of Internal Medicine, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, Pakistan.
Background: Missed abortion in the first trimester is characterized by the cessation of embryonic or fetal development while the cervix remains closed, often resulting in little to no bleeding. Ultrasound examinations typically reveal an empty gestational sac or an embryo/fetus that lacks cardiac activity. Misoprostol is the primary medication used to manage early pregnancy loss.
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