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Ribosome-lamella complexes in the peripheral blood of patients with chronic lymphocytic leukemia are associated with serological immune deficiency.
Ultrastruct Pathol
February 2010
Institute of Histology and Embryology, Faculty of Medicine, University of Belgrade, Visegradska 26, Belgrade, Serbia.
The ribosome-lamella complex (RLC) is a cylindrical structure composed of different numbers of circular lamellae with associated particles, regarded as ribosomes, around a central core. Structures resembling RLC, but lacking the typical mature appearance of RLC, have been called pre-RLC. The authors have found RLCs and pre-RLCs in peripheral lymphocytes of 3 patients with chronic lymphocytic leukemia (CLL).
View Article and Find Full Text PDFRibosome-lamella complexes in injured podocytes: description of a case and review of the literature.
Ultrastruct Pathol
October 2009
United Hospitals, Ancona, Italy.
Ribosome-lamella complexes (RLCs) are mainly observed in a variety of hematological disorders and occasionally in solid neoplasms and in nonneoplastic diseases. These intracytoplasmic organelles are held to arise from rough endoplasmic reticulum, but, in agreement with more recent literature data, their function is still unclear. Ultrastructural analysis of glomeruli from a patient with focal segmental glomerulosclerosis secondary to metabolic syndrome disclosed significant foot process loss and abundant cytoskeletal proteins in major podocyte processes; two of the latter also displayed RLCs.
View Article and Find Full Text PDFRibosome-lamella complex precursors in acute monocytic leukemia: a study of 6 cases.
Ultrastruct Pathol
August 2007
Institute of Hematology & Blood Diseases Hospital, Peking Union Medical College, Tianjin, China.
The ribosome-lamella complex (RLC) is a cylindrical structure composed of annular lamella associated particles, regarded as ribosomes, around a central core, which is best known in hairy cell leukemia. RLC has been presumed to originate from aggregating rER and ribosomes. Incomplete and maturing RLC structures have been called RLC precursors (pre-RLC).
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