Fosmidomycin-clindamycin therapy given every 12 h for 3 days was compared with a standard single oral dose of sulfadoxine-pyrimethamine. The two treatments showed comparably good tolerabilities and had an identical high degree of efficacy of 94% in a randomized trial carried out with 105 Gabonese children aged 3 to 14 years with uncomplicated malaria. These antimalarials merit further clinical exploration.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855537 | PMC |
| http://dx.doi.org/10.1128/AAC.01448-06 | DOI Listing |
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