We report a case of lupus erythematosus panniculitis with long-standing systemic lupus erythematosus. The patient developed widespread calcification and membrano-cystic changes in the subcutaneous tissue. There have been no reports of the coexistence of calcification and membrano-cystic changes in the literature. The mechanism for the coexistence of the calcification and membrano-cystic changes might be due to the degenerative changes in fat cells from local circulatory disturbance.

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