Electrodiagnostic studies are a critical tool for the identification and study of peripheral neuropathy, enabling definition of the pathophysiologic type of nerve injury, its distribution, severity, and the degree of motor or sensory nerve involvement. These data help to differentiate the varieties of neuropathy from other neuromuscular diseases. Nerve conduction studies and electromyography, although widely performed, are complex techniques and are subject to a wide range of artifacts, which can result in missed or erroneous diagnoses. Without proper education, training, and experience in neuromuscular disease and the techniques of electrodiagnosis and careful attention to potential sources of error, the critical information needed to properly diagnose and treat patients with neuropathy is unreliable and may lead to wasted resources and patient injury.
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http://dx.doi.org/10.1016/j.ncl.2007.01.011 | DOI Listing |
PLoS One
January 2025
Department of Biomedical Engineering, The Ohio State University, Columbus, OH, United States of America.
Traumatic optic neuropathy (TON) is a common cause of irreversible blindness following head injury. TON is characterized by axon damage in the optic nerve followed by retinal ganglion cell death in the days and weeks following injury. At present, no therapeutic or surgical approach has been found to offer any benefit beyond observation alone.
View Article and Find Full Text PDFJ Neurol
January 2025
Western Institute of Neuroscience, Western University, London, Canada.
Background: Repeat neurological assessment is standard in cases of severe acute brain injury. However, conventional measures rely on overt behavior. Unfortunately, behavioral responses may be difficult or impossible for some patients.
View Article and Find Full Text PDFJ Neurol
January 2025
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, China.
Background And Objective: Neuronal intranuclear inclusion disease (NIID) is a multifaceted disorder impacting both the central and peripheral nervous systems. This study aims to investigate the clinical and electrophysiological characteristics of peripheral neuropathy in patients with NIID.
Methods: In this cross-sectional study, patients diagnosed with NIID were prospectively recruited from multiple centers across China between October 2017 and May 2024.
Medicine (Baltimore)
November 2024
Department of Neurology, The People's Hospital of Suzhou New District, Suzhou, Jiangsu, China.
Rationale: Neuronal intranuclear inclusion disease (NIID) is a slowly progressing neurodegenerative disease with various manifestations and high heterogeneity. Clinical characteristics, imaging, skin biopsy, and genetic testing are necessary for its diagnosis. Electromyography may also be a useful tool for diagnosing NIID.
View Article and Find Full Text PDFInt J Environ Res Public Health
December 2024
Medical Centre Hospital of President's Affairs Administration of the Republic of Kazakhstan, Mangilik El 80, Astana 010000, Kazakhstan.
In clinical practice, heart rate variability (HRV) has not been considered an indicator for the preventive assessment of cardiovascular autonomic neuropathy (CAN). The paper studies HRV in a large, randomly selected group. A cross-sectional study included a representative sample of 5707 Kazakhs aged 20 years and older from a total population of 25,454 attached to an urban clinic in the capital of Kazakhstan.
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