Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800628 | PMC |
| http://dx.doi.org/10.1093/genetics/175.2.471 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Phase II Study of Acalabrutinib, Venetoclax, and Obinutuzumab in a Treatment-Naïve Chronic Lymphocytic Leukemia Population Enriched for High-Risk Disease.
J Clin Oncol
March 2025
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
Purpose: The AMPLIFY trial recently established fixed-duration acalabrutinib, venetoclax, and obinutuzumab (AVO) as a new standard-of-care option for patients with previously untreated chronic lymphocytic leukemia (CLL) with wild-type ; however, due to the chemoimmunotherapy control arm, AMPLIFY excluded patients with high-risk aberration, for whom current standards of care are continuous Bruton tyrosine kinase inhibitor therapy or alternatively fixed-duration venetoclax-based doublets. AVO has not previously been evaluated in patients with CLL with aberration.
Methods: This investigator-sponsored, multicenter, phase II study enrolled patients with treatment-naïve CLL enriched for high-risk CLL, defined by aberration (ClinicalTrials.
Feasibility and acceptability of a telerehabilitation intervention on patients undergoing total knee arthroplasty in Iran: randomised controlled trial protocol.
BMJ Open
June 2024
Department of Orthopedic Surgery, Aja University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
Introduction: Telerehabilitation is a promising avenue to enhance post-total knee arthroplasty (TKA) rehabilitation by improving accessibility, convenience and cost-effectiveness. Despite its potential benefits, its application in the context of TKA in Iran is in its early stages, lacking comprehensive studies on feasibility, acceptance and programme adherence. This article outlines a protocol for an open-label, parallel-group, randomised controlled trial investigating the impact of a 4 week telerehabilitation programme alongside usual care.
View Article and Find Full Text PDFIncidence, risk factors, and outcomes of acute kidney injury in patients undergoing emergency laparotomy - A prospective observational exploratory study.
Indian J Anaesth
February 2024
Department of Obstetrics and Gynaecology, AIIMS, Bibinagar, Hyderabad, Telangana, India.
Background And Aims: Acute kidney injury (AKI) can occur in post-laparotomy patients, with a variable incidence. This study aimed to determine the incidence of AKI in patients undergoing emergency laparotomy under general anaesthesia, the effect of preoperative variables on the development of AKI, and the association of post-operative AKI with patient outcomes.
Methods: This prospective exploratory study in patients undergoing emergency laparotomy was followed up for 7 days to determine the incidence of post-operative AKI.
Impact of mental health comorbidity in children and young adults with inflammatory bowel disease: a UK population-based cohort study.
BMJ Open
February 2024
Department of Paediatric Gastroenterology, Royal Hospital for Children and Young People, Edinburgh, UK
Objective: To evaluate the impact of mental health comorbidity in children and young adults with inflammatory bowel disease (IBD).
Design: Retrospective observational study.
Setting: Representative population, routinely collected primary care data from the UK Optimum Patient Care Research Database (2015-2019).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!