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NeuroMix with MRA: A Fast MR Protocol to Reduce Head and Neck CTA for Patients with Acute Neurologic Presentations.

AJNR Am J Neuroradiol

November 2024

From the Division of Neuroimaging and Neurointervention (J.H.D., A.T.M., A.B., N.F., G.Z.), Department of Radiology, Stanford University, Stanford, California.

Article Synopsis
  • Overuse of CT angiography (CTA) for minor neurological issues can cause unnecessary radiation exposure and may require follow-up MRI for proper diagnosis.
  • A study evaluated the effectiveness of a fast MRI protocol called NeuroMix, combined with MRA, against CTAH for patients within 24 hours, with results indicating that the MRI approach was equivalent or superior in most cases.
  • The findings suggest that the new MRI techniques can provide better or similar diagnostic information in 95% of instances, reducing reliance on CTA for certain patient populations.
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Background: Wall shear stress (WSS) has been proved to be related to the formation, development and rupture of intracranial aneurysms. Aneurysm wall enhancement (AWE) on magnetic resonance imaging (MRI) can be caused by inflammation and have confirmed its relationship with low WSS. High WSS can also result in inflammation but the research of its correlation with AWE is lack because of the focus on large aneurysms limited by 3T MRI in most previous studies.

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Background And Purpose: Carotid atherosclerotic plaques with a large lipid-rich necrotic core (LRNC), intraplaque hemorrhage (IPH), and a thin or ruptured fibrous cap are associated with increased stroke risk. Multi-sequence MRI can be used to quantify carotid atherosclerotic plaque composition. Yet, its clinical implementation is hampered by long scan times and image misregistration.

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Article Synopsis
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 The purpose of this study is to evaluate magnetic resonance (MR) angiography (MRA) and venography (MRV) findings in tuberculous meningitis (TBM).  Thirty consecutive patients of clinically diagnosed TBM were enrolled. Apart from T2-weighted imaging, T1-weighted imaging (T1WI), diffusion-weighted imaging, susceptibility-weighted imaging, fluid-attenuated inversion recovery, and postcontrast T1WI, time-of-flight (TOF) MRA and postcontrast MRV were done in all the patients.

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