AI Article Synopsis
- Salivary duct carcinoma (SDC) is an aggressive type of cancer primarily found in the parotid and submandibular glands, with rare occurrences in the mandible.
- A 62-year-old man diagnosed with SDC in the mandible experienced a painless lump and nerve palsy; surgery revealed metastasis in lymph nodes.
- After undergoing surgery, radiation, and chemotherapy, the patient survived for 59 months, though he faced local recurrence and metastases to the lung and brain.
Article Abstract
Salivary duct carcinoma (SDC) is a distinctive and aggressive neoplasm. The most frequent site of origin is the parotid gland, followed by the submandibular gland. SDC originating in the minor salivary glands, particularly in the ectopic glands within the mandible, is extremely rare. We describe a 62-year-old man with SDC in the mandible, who presented with a painless lump in the right submandibular region (later identified as lymph node metastasis) and ipsilateral mental nerve palsy. Histologic examination after ablative surgery revealed SDC originating in the mandible and cervical nodal metastases spreading to levels I-III. The patient remains alive 59 months after presentation as a result of postoperative full-dose irradiation and regular intensive chemotherapy using TXT, 5-FU, and CDDP. However, the patient has local recurrence and distant metastases to the lung and brain. In this report, we also discuss the specific diagnostic criteria and developmental theories of intraosseous salivary gland tumors.
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| http://dx.doi.org/10.1016/j.tripleo.2006.01.004 | DOI Listing |
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