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CaV1.3 enhanced store operated calcium promotes resistance to androgen deprivation in prostate cancer.
Cell Calcium
May 2022
DCU Cancer Research Group, DCU, Ireland; National Institute Cellular Biotechnology, DCU, Ireland; School of Nursing, Psychotherapy and community health, DCU, Ireland. Electronic address:
Androgen deprivation therapy (ADT) is the main treatment for advanced prostate cancer (PCa) but resistance results in progression to terminal castrate resistant PCa (CRPC), where there is an unmet therapeutic need. Aberrant intracellular calcium (Ca) is known to promote neoplastic transformation and treatment resistance. There is growing evidence that voltage gated calcium channel (VGCC) expression is increased in cancer, particularly CACNA1D/CaV1.
View Article and Find Full Text PDFHigh blood pressure readings on in-store machines: a qualitative study of the perspective of pharmacy staff.
J Pharm Policy Pract
February 2021
Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Objectives: Emergency department (ED) visits for high blood pressure are on the rise. Yet the majority of these patients are discharged home after their ED evaluation, particularly those who present following an elevated reading on an in-store pharmacy machine. We aimed to gain insight on the practice and referral patterns of pharmacy staff who encounter a patient with an elevated in-store blood pressure (BP) reading.
View Article and Find Full Text PDFThe impact of emotions on shopping behavior during epidemic. What a business can do to protect customers.
J Consum Behav
August 2020
Department of Animal Products Technology, Faculty of Food Technology University of Agriculture in Kraków Kraków Poland.
The study investigated how the perception of in-shop COVID-19 contraction influences emotions in decision-making and how they further effect actions undertaken by consumers to control the situation within a store. Structural equation modeling was used to study the relationship between the risk of in-store infection, emotions and in-shop behavior, based on data retrieved from 914 questionnaires. Results showed, that the perceived risk of becoming infected in a store causes an increase in arousal and, at the same time, a decrease in perceived pleasure during shopping.
View Article and Find Full Text PDFChanges in the UK baby food market surveyed in 2013 and 2019: the rise of baby snacks and sweet/savoury foods.
Arch Dis Child
December 2020
Department of Child Health, University of Glasgow College of Medical Veterinary and Life Sciences, Glasgow, UK.
Objective: To assess how the baby food market in the UK has changed between 2013 and 2019.
Setting: United Kingdom.
Design: A cross-sectional survey of all infant food products available to buy in the UK online and in-store collected in 2019.
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