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Gastrinoma (duodenal and pancreatic). | LitMetric

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http://dx.doi.org/10.1159/000098009DOI Listing

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Article Synopsis
  • - A gastrinoma is a rare but serious tumor that produces gastrin, which can cause symptoms like anemia, weight loss, and diarrhea, complicating early detection.
  • - These tumors often spread to the liver, and surgery is typically necessary to remove both the primary tumor and any metastases for a chance at a cure.
  • - This report discusses a case involving a 59-year-old woman with anemia and gastrointestinal bleeding, revealing a pancreatic gastrinoma with extensive liver metastases, along with the treatment approach taken to improve her survival odds.
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Middle-segment preserving pancreatectomy: a literature review and case report.

Langenbecks Arch Surg

June 2024

Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.

Article Synopsis
  • Middle segment-preserving pancreatectomy (MSPP) is a newer surgical option for treating benign and borderline pancreatic diseases, offering an alternative to total pancreatectomy (TP), with only 36 reported cases so far.
  • In a case study of a 49-year-old man with Zollinger-Elison syndrome, MSPP was successfully performed, resulting in a postoperative pancreatic fistula that improved with conservative care, and no tumor recurrence was observed.
  • Although MSPP has a high morbidity rate (54%) primarily due to complications like pancreatic fistula, it shows low mortality rates and maintains pancreatic function similar to traditional surgeries.
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Article Synopsis
  • * A 40-year-old patient with long-term epigastric pain and diarrhea was diagnosed with ZES after undergoing imaging and biopsy, revealing a gastrinoma.
  • * Surgical removal of the gastrinoma is the most effective treatment for ZES, and early diagnosis is crucial for managing symptoms like chronic diarrhea and abdominal pain.
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Article Synopsis
  • A 54-year-old man with obesity, hypertension, and a long history of abdominal pain underwent various medical tests over 12 years, revealing multiple ulcers but no clear diagnosis initially.
  • In 2022, he was diagnosed with gastrinoma, a type of neuroendocrine tumor, after advanced imaging techniques identified a lesion not visible on CT scans.
  • The report emphasizes the need to consider neuroendocrine tumors in similar cases and supports using 68Ga-DOTATOC PET/CT scans over older imaging methods for accurate diagnosis.
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