Method: This study examines group and individual performance on word list recall and recognition in 52 patients with unilateral right hemisphere stroke.
Results: On the California Verbal Learning Test, List A, Trials 1-5, patients achieved a mean score of 30.31 (SD = 13.94), which is below the mean standard score of 50 (SD = 10) in a normal population. Patients demonstrated below-average performance on other immediate and delayed recall trials and on free- and cued-recall tasks. 67% of patients showed improved performance across learning trials.
Conclusion: Results provide support for encoding deficits with reduced rate of learning and inconsistent recall across trials.
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http://dx.doi.org/10.1310/tsr1401-13 | DOI Listing |
J Gerontol B Psychol Sci Soc Sci
January 2025
Herbert and Jacqueline Krieger Klein Alzheimer's Research Center, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Objectives: The oldest old adults (90+) constitute the fastest growing demographic at highest dementia risk among older adults. Depression, a common risk factor, inherently presents with heterogeneous clinical manifestations. Here, we explored the associations of the predominant depression dimensions with cognition in the LifeAfter90 study.
View Article and Find Full Text PDFAlzheimers Dement
January 2025
Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
Introduction: We compared the relationship between offspring education and cognitive health outcomes among Hispanic and White adults.
Methods: We used data from Hispanic and White (1998-2018) United States (US) Health and Retirement Study (HRS) participants (n = 17,484). We assessed cognitive function and decline using episodic memory scores in linear mixed models and incident cognitive impairment with no dementia (CIND) or probable dementia using the Langa-Weir 27-point-scale in Cox proportional hazards models.
Transl Psychiatry
January 2025
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Peripheral inflammatory markers (PIMs), such as C-reactive protein (CRP) or white blood cell count (WBC), have been associated with depression severity in meta-analyses and large cohort studies. However, in typically-sized psychoimmunology studies (N < 200) that explore associations between PIMs and neurobiological/psychosocial constructs related to depression and studies that examine less-studied PIMs (e.g.
View Article and Find Full Text PDFBMC Genomics
January 2025
Program in Public Health, College of Health Sciences, University of California, Irvine, California, USA.
Background: The resurgence of Anopheles funestus, a dominant vector of human malaria in western Kenya was partly attributed to insecticide resistance. However, evidence on the molecular basis of pyrethroid resistance in western Kenya is limited. Here, we reported metabolic resistance mechanisms and demonstrated that multiple non-coding Ribonucleic Acids (ncRNAs) could play a potential role in An.
View Article and Find Full Text PDFCase Rep Genet
January 2025
Medical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California, 2825 50th Street, Davis, Sacramento 95817, California, USA.
Fragile X syndrome (FXS) presents with autism spectrum disorder (ASD), intellectual disability, developmental delay, seizures, hypotonia during infancy, joint laxity, behavioral issues, and characteristic facial features. The predominant mechanism is due to CGG trinucleotide repeat expansion of more than 200 repeats in the 5'UTR (untranslated region) of (Fragile X Messenger Ribonucleoprotein 1) causing promoter methylation and transcriptional silencing. However, not all patients presenting with the characteristic phenotype and point/frameshift mutations with deletions in have been described in the literature.
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