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http://dx.doi.org/10.1021/jp067486b | DOI Listing |
Am J Cardiovasc Drugs
January 2025
Springer Nature, Private Bag 65901, Mairangi Bay, Auckland, 0754, New Zealand.
Flurpiridaz F 18 (FLYRCADO™) is an intravenous (IV) radioactive diagnostic drug being developed by GE Healthcare and Lantheus Medical Imaging for use in positron emission tomography (PET) myocardial perfusion imaging (MPI) to detect coronary artery disease (CAD). In September 2024, flurpiridaz F 18 was approved in the USA for PET MPI under rest or stress (pharmacologic or exercise) in adult patients with known or suspected CAD to evaluate for myocardial ischemia and infarction. This article summarizes the milestones in the development of flurpiridaz F 18 leading to this first approval for use in PET MPI in adult patients to evaluate for myocardial ischemia and infarction.
View Article and Find Full Text PDFBiosensors (Basel)
January 2025
College of Engineering, Huazhong Agricultural University, Wuhan 430070, China.
The increasing demand for smart agriculture has led to the development of agricultural sensor technology. Wearable sensors show great potential for monitoring the physiological and surrounding environmental information for plants due to their high flexibility, biocompatibility, and scalability. However, wearable sensors for plants face several challenges that hinder their large-scale practical application.
View Article and Find Full Text PDFNPJ Antimicrob Resist
March 2024
Institute of Life Sciences, Medical School, Swansea University, Singleton Park, Swansea, SA2 8PP, Wales, UK.
The discoveries of penicillin and streptomycin were pivotal for infection control with the knowledge subsequently being used to enable the discovery of many other antibiotics currently used in clinical practice. These valuable compounds are generally derived from mesophilic soil microorganisms, predominantly Streptomyces species. Unfortunately, problems with the replication of results suggested that this discovery strategy was no longer viable, motivating a switch to combinatorial chemistry in conjunction with existing screening programmes to derive new antimicrobials.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
December 2024
Department of Epidemiology, School of Public Health, Fudan University; Key Laboratory of Public Health Safety, Ministry of Education; Tropical Disease Research Center, Fudan University, Shanghai 200032, China.
The rapid development of artificial intelligence poses a huge impact on health and has become a core driving force for the new generation of the scientific and technological revolution in the field of healthcare. Recently, artificial intelligence has been gradually applied in the field of parasitic diseases and parasitology, including disease diagnosis, prognosis prediction, prediction of transmission risk, intelligent identification of vectors and intermediate hosts, and disease prevention and control, which facilitates the progress towards elimination of parasitic diseases. In addition, artificial intelligence provides highly efficient tools and approaches for healthcare workers and researchers.
View Article and Find Full Text PDFObes Rev
January 2025
Department of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
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