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Coalescence of B cell receptor and invariant chain MHC II in a raft-like membrane domain.
J Leukoc Biol
November 2014
Hannover Medical School, Department of Cell Biology, Center for Anatomy, Hannover, Germany
The BCR binds antigen for processing and subsequent presentation on MHC II molecules. Polyvalent antigen induces BCR clustering and targeting to endocytic processing compartments, which are also accessed by Ii-MHC II. Here, we report that clustered BCR is able to team up with Ii-MHC II already at the plasma membrane of mouse B-lymphocytes.
View Article and Find Full Text PDFRaftlike polyvalent inhibitors of the anthrax toxin: modulating inhibitory potency by formation of lipid microdomains.
Angew Chem Int Ed Engl
June 2007
Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
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