Efficient methodology for selective alkylation of hydrazine derivatives.

Org Lett

Institute of Organic and Bioorganic Chemistry, University of Tartu, Jakobi 2, 51014 Tartu, Estonia.

Published: March 2007

Formation and use of a nitrogen dianion for selective hydrazine alkylation is reported. The scope and limitations of a new method were demonstrated. The novel method provides fast and easy access to substituted hydrazines, which are widely used as drugs, pesticides, and precursors for a variety of compounds in organic synthesis. [reaction: see text]

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Source
http://dx.doi.org/10.1021/ol070026wDOI Listing

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