Although much is known about the relationship between neuropsychiatric problems and the severity of cognitive impairments, relatively little is known about the association with specific cognitive impairments. The aim of this study was to determine whether specific cognitive impairments are predictive of neuropsychiatric problems. One hundred twenty-six patients were evaluated every 6 months for 2 years. In particular, a low level of language expression was related to higher levels of overall neuropsychiatric problems and to psychosis. Impairment of abstract reasoning was related to psychosis and aberrant motor behavior.
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http://dx.doi.org/10.1176/jnp.2007.19.1.50 | DOI Listing |
Background: While aerobic exercises have demonstrated efficacy in slowing cognitive decline and improving psychological symptoms associated with cognitive impairments, they may not be feasible due to multiple disabilities. Other gentle exercises with mindful approaches, such as "Yoga-like", have been explored but lack clear evidence.
Aim: To assess the efficacy of a "Yoga-like" intervention on cognitive and psychological features in patients with mild to moderate Alzheimer Disease (AD).
Eur J Pediatr
January 2025
Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.
Unlabelled: Klinefelter syndrome (KS) is the most common sex chromosomal aneuploidy in males (47,XXY karyotype in 80-90% of cases), primarily characterized by hypergonadotropic hypogonadism and infertility. It encompasses a broad phenotypic spectrum, leading to variability in neurocognitive and psychosocial outcomes among affected individuals. Despite the recognized correlation between KS and various neuropsychiatric conditions, studies investigating potential sleep disorders, particularly in pediatric subjects, are lacking.
View Article and Find Full Text PDFInt J Ment Health Nurs
February 2025
Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.
Knowledge is needed about end-of-life care among patients with pre-existing severe mental disorders: Schizophrenia, bipolar disorder, and depression. This study aimed to explore the experiences with end-of-life care for patients with severe mental disorders, their relatives, specialised palliative care nurses and physicians, and general practitioners. Twenty semi-structured interviews were conducted and analysed using reflexive thematic analysis, hereby six interviews with patients, three with relatives, five with general practitioners, and six with specialised palliative healthcare professionals.
View Article and Find Full Text PDFIndian J Pediatr
January 2025
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Objectives: To determine the prevalence of psychiatric morbidities in survivors of pediatric acute lymphoblastic leukemia (ALL) and to identify any risk factors.
Methods: Survivors of ALL, who had completed their treatment, atleast two or more years ago and now were 6-18 y old were enrolled on the study. The Mini International Neuropsychiatric Interview (M.
Introduction: Anthropometric, demographic, genetic, and clinical features may affect cognitive, behavioral, and functional decline, while clinical trials seldom consider minimal clinically important differences (MCIDs) in their analyses.
Methods: MCIDs were reviewed taking into account features that may affect cognitive, behavioral, or functional decline in clinical trials of new disease-modifying therapies.
Results: The higher the number of comparisons of different confounders in statistical analyses, the lower values will be significant.
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