Objective: The study focused on the correlation between maternal polymorphisms of genes encoding antioxidant enzymes and the risk of having a child with CL/P in the Polish population.
Method: PCR-RFLP analysis was used to analyze polymorphisms of MnSOD2 (c.47T>C), CAT (c.-330C>T) and GPX1 (c.599C>T) in mothers of children with CL/P and control mothers.
Results And Conclusion: Polymorphic variants of genes for main antioxidant enzymes were determined not to be a maternal risk factor for having a child with CL/P in the investigated group of women.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.clinbiochem.2006.11.023 | DOI Listing |
Publication Analysis
Top Keywords
antioxidant enzymes
12
polymorphic variants
8
variants genes
8
genes encoding
8
main antioxidant
8
enzymes risk
8
child cl/p
8
encoding main
4
risk cl/p-affected
4
cl/p-affected pregnancies
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!