How much solute is needed to inhibit the fluid to gel membrane phase transition at low hydration?

Biochim Biophys Acta

Applied Physics, School of Applied Sciences, RMIT University, Melbourne, Australia.

Published: May 2007

We present a quantitative study of the effect of sugars on the membrane gel-fluid phase transition as a function of sugar:lipid ratio. We show that the maximum effect occurs at around 1.5 sugar rings per molecule for both mono- and di-saccharides. We present a theoretical model to try to explain these results, and discuss the assumptions inherent in the model.

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http://dx.doi.org/10.1016/j.bbamem.2007.01.008DOI Listing

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