AI Article Synopsis

  • Two expert microscopists diagnosed malaria infections in over 2,100 adults in Thailand and Peru during multiple field studies from 1998 to 2001.
  • Plasmodium vivax patients with gametocytemia had higher fevers and parasite levels compared to those without it, while Plasmodium falciparum patients with gametocytemia experienced lower fevers but similar parasitemia.
  • Hematology results showed that P. vivax patients with gametocytemia had lower platelet counts, whereas P. falciparum patients had similar platelet counts but lower red blood cell, hemoglobin, and hematocrit levels, with increased lymphocyte counts.

Article Abstract

Two expert research microscopists, each blinded to the other's reports, diagnosed single-species malaria infections in 2,141 adults presenting at outpatient malaria clinics in Tak Province, Thailand, and Iquitos, Peru, in May-August 1998, May-July 1999, and May-June 2001. Plasmodium vivax patients with gametocytemia had higher fever and higher parasitemia than those without gametocytemia; temperature correlated with parasitemia in the patients with gametocytemia. Plasmodium falciparum patients with gametocytemia had lower fever than those without gametocytemia, but similar parasitemia; temperature correlated with parasitemia in the patients without gametocytemia. Hematologic data in Thailand in 2001 showed lower platelet counts in P. vivax patients with gametocytemia than in the P. vivax patients without gametocytemia, whereas P. falciparum patients with gametocytemia had similar platelet counts but lower red blood cell counts, hemoglobin levels, hematocrit levels, and higher lymphocyte counts than patients without gametocytemia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500222PMC
http://dx.doi.org/10.1645/GE-911R.1DOI Listing

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