Seven new steroidal glycosides from the roots of Cynanchum forrestii.

Steroids

Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Peking Union Medical College, Beijing 100050, People's Republic of China.

Published: April 2007

Seven new steroidal glycosides, cynaforrosides K (1), L (2), M (3), N (4), and Q (7), based on a 13,14:14,15-disecopregnane-type aglycone, and cynaforrosides O (5) and P (6) with a 14,15-secopregnane-type aglycone, were isolated from the 95% ethanol extract of the roots of Cynanchum forrestii Schlechter. The structures of new compounds were determined on the basis of spectroscopic and chemical evidence. The sugar units of cynaforrosides K-P contained two moieties of glucoses with the mode of 1-->4 linkage and those of cynaforrosides K-O contained six moieties of sugars.

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http://dx.doi.org/10.1016/j.steroids.2006.11.024DOI Listing

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