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Epidemiology and Antimicrobial Resistance of Stenotrophomonas maltophilia in China, 2014-2021.
Infect Dis Ther
December 2024
Department of Respiratory Medicine, The First Affiliated Hospital of Wannan Medical College, No 2 Zheshan West Road, Wuhu, 241000, Anhui, China.
Introduction: Stenotrophomonas maltophilia is an opportunistic pathogen associated with various nosocomial infections and is known for its intrinsic multidrug resistance. This study aims to provide a comprehensive overview of the epidemiology and resistance patterns of S. maltophilia in China from 2014 to 2021.
View Article and Find Full Text PDFGenomic analysis and virulence of human Streptococcus suis serotype 14.
Eur J Clin Microbiol Infect Dis
December 2024
Faculty of Public Health, Kasetsart University Chalermphrakiat Sakon Nakhon Province Campus, Sakon Nakhon, Thailand.
Purpose: Streptococcus suis serotype 14 is the second most prevalent serotype being highly prevalent in Southeast Asia. This study aimed to characterize genetic background, population structure, virulent genes, antimicrobial-resistant genes, and virulence of human S. suis serotype 14.
View Article and Find Full Text PDFPiezoresistive Sensor Based on Porous Sponge with Superhydrophobic and Flame Retardant Properties for Motion Monitoring and Fire Alarm.
ACS Appl Mater Interfaces
December 2024
College of Chemistry and Chemical Engineering, Xi'an University of Science and Technology, Xi'an 710054, China.
Polyurethane sponge is frequently selected as a substrate material for constructing flexible compressible sensors due to its excellent resilience and compressibility. However, being highly hydrophilic and flammable, it not only narrows the range of use of the sensor but also poses a great potential threat to human safety. In this paper, a conductive flexible piezoresistive sensor (CHAP-PU) with superhydrophobicity and high flame retardancy was prepared by a simple dip-coating method using A-CNTs/HGM/ADP coatings deposited on the surface of a sponge skeleton and modified with polydimethylsiloxane.
View Article and Find Full Text PDFOncolytic measles virus-induced cell killing in radio-resistant and drug-resistant nasopharyngeal carcinoma.
Malays J Pathol
December 2024
Universiti Tunku Abdul Rahman, M. Kandiah Faculty of Medicine and Health Sciences, Department of Pre-clinical Sciences, Bandar Sungai Long, 43000, Kajang, Selangor, Malaysia.
Introduction: The current first-line therapy for nasopharyngeal carcinoma (NPC) is often associated with long-term complications. Oncolytic measles virus (MV) therapy offers a promising alternative to cancer therapy. This study aims to investigate the efficacy of MV in killing NPC cells in vitro, both with or without resistance to radiation and drug therapy.
View Article and Find Full Text PDFAutophagy Modulates Glioblastoma Cell Sensitivity to Selinexor-mediated XPO1 inhibition.
Neuro Oncol
December 2024
Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Background: Selinexor is a selective inhibitor of exportin-1 (XPO1), a key mediator of the nucleocytoplasmic transport for molecules critical to tumor cell survival. Selinexor's lethality is generally associated with the induction of apoptosis, and in some cases, with autophagy-induced apoptosis. We performed this study to determine Selinexor's action in glioblastoma (GBM) cells, which are notoriously resistant to apoptosis.
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