Purpose: Premature ejaculation is characterized by short ejaculatory latency, inability to control ejaculation and resultant overall decreased sexual satisfaction for the man and his partner. Diagnostic criteria typically include aspects of psychological well-being. To motivate and justify treatment for premature ejaculation a more comprehensive understanding of its impact on men, their partners and their overall relationship is needed.
Materials And Methods: In a community based, observational study of 1,587 men and their female partners clinicians diagnosed premature ejaculation using Diagnostic and Statistical Manual of Mental Disorders, 4th edition, text revision criteria. For purposes of this analysis this group was further restricted to subjects with a stopwatch measured intravaginal ejaculatory latency time of 2 minutes or less. Responses to the Premature Ejaculation Profile, Self-Esteem and Relationship questionnaire, Golombok-Rust Inventory of Sexual Satisfaction and Medical Outcomes Study SF-36 were compared between premature ejaculation and nonpremature ejaculation groups. Correlations between responses of men and partners were assessed for the Premature Ejaculation Profile and Golombok-Rust Inventory of Sexual Satisfaction. Correlations among patient reported measures enabled the assessment of independence of outcome variables.
Results And Conclusions: Of 207 men who met Diagnostic and Statistical Manual of Mental Disorders, 4th edition, text revision criteria 89 had an intravaginal ejaculatory latency time of 2 minutes or less. Lower levels of sexual functioning and satisfaction, and higher levels of personal distress and interpersonal difficulty were reported by men with premature ejaculation and their partners. In addition, men with premature ejaculation rated their overall quality of life lower than that of men without premature ejaculation. Consequently premature ejaculation has a significant psychological burden on men, their partners and the male/partner relationship.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.juro.2006.10.025 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Association Between Fine Particle Waves and Sexual Function: A Nationwide Cross-Sectional Survey in China.
Toxics
January 2025
Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Background: The effect of the long-term persistently elevated air pollutants, often referred to as air pollution waves, on sexual function has not been sufficiently addressed.
Methods: This nationwide cross-sectional study involved 12,157 participants, with 5496 females and 5039 males. PM waves were characterized by daily average PM concentrations surpassing Grade II thresholds of China's ambient air quality standards (PM > 75 μg/m, PM > 150 μg/m) for three or more consecutive days (3-8 days).
Two studies, two outcomes: botulinum toxin in lifelong premature ejaculation treatment.
Asian J Androl
January 2025
Department of Urology, Biruni University, İstanbul 34015, Türkiye.
From spermatogenesis to fertilisation: the role of melatonin on ram spermatozoa.
Domest Anim Endocrinol
January 2025
BIOFITER-IUCA, Universidad de Zaragoza, Facultad de Veterinaria, Miguel Servet 177, 50013 Zaragoza, Spain. Electronic address:
This review presents recent findings on the effect of melatonin on ram spermatozoa. This hormone regulates seasonal reproduction in the ovine species through the hypothalamic-pituitary-gonadal axis, but it also exerts direct effects on spermatogenesis, seminal quality and fertility. In the testis, melatonin stimulates blood flow to this organ, but it also appears to be involved in the differentiation of spermatogonial stem cells and the secretion of testosterone through the MT1 and MT2 receptors.
View Article and Find Full Text PDFDevelopment and in vitro/in vivo evaluation of taste-masked orodispersible films of dapoxetine hydrochloride using ion exchange resins.
Drug Deliv Transl Res
January 2025
Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410006, Hunan, China.
Dapoxetine hydrochloride tablets are the most commonly used drug for the treatment of premature ejaculation (PE). However, the tablets must be taken with water 1-3 h before sexual activity, which makes the medication intake conspicuous and inconvenient. This study aimed to develop taste-masked orodispersible films (ODFs) of dapoxetine hydrochloride using ion exchange resins.
View Article and Find Full Text PDFA New and Safe Delivery of Sildenafil Citrate Co-Evaporate Loaded Emulgels for the Cure of Certain Male Sexual Dysfunctions.
AAPS PharmSciTech
January 2025
Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Assiut University, Assiut, Egypt.
The present work focuses on the production of sildenafil co-evaporates loaded emulgels as topical dosage forms for the treatment of premature ejaculation and erectile dysfunction. Topical administration of sildenafil citrate (SILD) co-evaporates is expected to improve the bioavailability profile of the drug and to avoid the severe side effects accompanying the traditional SILD dosage forms, especially for prohibited cardiovascular cases. Firstly, the solubility of SILD was improved via solid dispersion via co-evaporation technique using PEG-5KDa and PVP-K90 as hydrophilic carriers.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!