Purpose: Complications associated with placement of artificial urinary sphincter may make reoperation necessary. We present a surgical description and outcome data for tandem transcorporal artificial urinary sphincter salvage technique for nonmechanical artificial urinary sphincter failure.
Materials And Methods: A retrospective analysis from July 2002 to December 2005 identified 198 consecutive men who underwent artificial urinary sphincter placement by a single surgeon (DSE) for postoperative stress urinary incontinence. Tandem transcorporal salvage artificial urinary sphincter surgery was performed in 18 patients with 1 (10 of 18) or both (8 of 18) cuffs placed transcorporally. Etiology of previous artificial urinary sphincter failure leading to the insertion of both cuffs in the transcorporal position included 3 infections, 2 erosions, 2 impending erosions, and 1 failed male sling. A self-administered standardized questionnaire was used to assess continence and quality of life outcomes.
Results: At a median followup of 26 months (IQR 14 to 30), pad use decreased from a median of 5.0 (IQR 3.5 to 5) to 2.0 (IQR 1 to 3) (p<0.001). Two patients experienced explantation of the device (1 erosion, 1 infection) without reimplantation and, thus, were excluded from outcome analysis. Eleven (69%) required 2 or fewer pads daily, and 5 (31%) required 3 pads daily. Eleven (69%) reported being very or extremely improved. Of the 5 patients reporting some or no improvement 4 were also on androgen deprivation therapy, suggesting that the transcorporal technique may be less durable in this group of patients.
Conclusions: Tandem transcorporal artificial urinary sphincter placement is an effective approach to salvage cases with a high risk of repeat erosion or infection after failed artificial urinary sphincter placement.
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http://dx.doi.org/10.1016/j.juro.2006.10.052 | DOI Listing |
Int J Impot Res
January 2025
Department of Urology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.
Prostate cancer treatment-related erectile dysfunction and stress urinary incontinence are commonly treated with inflatable penile prosthesis (IPP) or artificial urinary sphincter (AUS). Given the association with androgens and penile/urethral health, we aim to evaluate whether patients on androgen deprivation therapy (ADT) undergoing IPP or AUS surgery are at increased risk for reintervention, complication, or infection. We queried the TriNetX database for adult males receiving IPP or AUS.
View Article and Find Full Text PDFObjectives: To analyse and compare the functionality of extraluminal and intraluminal artificial urinary sphincters (AUSs), an in silico procedure has been defined and applied. Design and reliability assessments of the AUS are typically performed using a clinical approach, which does not provide data on mechanical stimulation of urethral tissues. Mechanical stimulation may determine tissue degeneration, such as urethral atrophy or erosion, the main causes of AUS failure.
View Article and Find Full Text PDFUrol Pract
December 2024
Urology Division, Hartford HealthCare Medical Group, Hartford, Connecticut.
Urol Pract
December 2024
Department of Urology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania.
Anal Chem
January 2025
School of Environmental & Chemical Engineering, Jiangsu University of Science and Technology, Changhui Rd. 666, Zhenjiang, Jiangsu 212003, China.
Early diagnosis of tumors allows effective treatment of primary cancers through localized therapeutic interventions. However, developing diagnostic tools for sensitive, simple, and early tumor (especially less than 2 mm in diameter) detection remains a challenge. Herein, we presented a biomarker-activatable nanoprobe that enabled a near-infrared (NIR) photothermally amplified signal for fluorescence imaging and urinalysis of tumor.
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