Objective: To compare the capacity of a reciprocating system (Endo-Gripper) and a rotary system (Profile .04) for mechanical removal of root-filling material from curved root canals in vitro.
Materials And Methods: Eighty canals (40 mesiobuccal and 40 mesiolingual) from mandibular first molars were instrumented and had their roots filled. After 6 months, 3-dimensional images of the roots were obtained by computed tomography (CT), and the volume of root-filling mass was measured. Root fillings were removed by either the reciprocating system with K-type files or the rotary system with NiTi files. The volume of filling debris remaining after the removal procedures was assessed by CT. The data were analyzed statistically by analysis of variance.
Results: Neither system completely removed the root-filling material. No significant differences were observed between the reciprocating and rotary systems in terms of the volume of filling material left within the canals after mechanical instrumentation. The volume of filling debris remaining was significantly lower for mesiolingual canals than for mesiobuccal canals.
Conclusions: Currently available mechanical systems are unable to completely remove filling material during retreatment. Use of the "threshold" function of the CT software allowed precise outlining of the remnants of filling material and calculation of its volume.
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Sci Rep
January 2025
Department of Environmental Technology, Faculty of Environment and Resource Studies, Mahasarakham University, Mahasarakham, 44150, Thailand.
Chicken eggshell waste is an alternative renewable source for quicklime production. Eggshell waste has received significant attention from researchers due to it being a potential source of bio-CaO, which not only drives the circular economy concept but also supports sustainable development. However, experiments on the production of bio-CaO are normally conducted in a small lab-scale furnace.
View Article and Find Full Text PDFDiabetol Metab Syndr
January 2025
Department of Pharmacy, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Background: Our meta-analysis fills gaps by assessing sodium-glucose cotransporter-2 (SGLT2) inhibitors' renal outcomes in chronic kidney disease (CKD) patients including long-term effects and the subgroup analyses of estimated glomerular filtration rate (eGFR) values and follow-up times.
Methods: The literature search of relevant randomized controlled trials (RCTs) was conducted in Medline, Embase, and the Cochrane Central from the inception to 8 June 2023 on patients with CKD treated with SGLT2 inhibitors. We selected medical subject heading (MeSH) terms and free text terms associated with gliflozin and RCT.
Int J Pharm
January 2025
Amgen Inc., Process Development, Manufacturing Technology Advancement (MTA) Group, Thousand Oaks, CA 91320, USA. Electronic address:
The inspection of liquid-filled vials and syringes using automated visual inspection (AVI) machines is a common practice in pharmaceutical production lines. Liquid drug products are typically agitated using a spin-stop motion to detach particles from the interior surface of the containers, thereby maximizing the probability of their detection. A numerical model for an ISO 8362-1 6R glass vial was developed and validated to qualitatively assess the agitation process for a range of motion profiles, liquid drug product properties, and fill volumes.
View Article and Find Full Text PDFJ Environ Manage
January 2025
Wuxi Fisheries College, Nanjing Agricultural University, 214081, Wuxi, PR China; Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, 214081 Wuxi, PR China; Laboratory of Quality & Safety Risk Assessment for Aquatic Products on Environmental Factors (Wuxi), Ministry of Agriculture and Rural Affairs, 214081, Wuxi, PR China; Key Laboratory of Control of Quality and Safety for Aquatic Products, Ministry of Agriculture and Rural Affairs, 100000, Beijing, PR China; Key Laboratory of Freshwater Fisheries and Germplasm Resources Utilization, Ministry of Agriculture and Rural Affairs, Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, 214081, Wuxi, PR China. Electronic address:
The presence of residual antibiotics in water constitutes a potential threat to aquatic environments. Therefore, designing environmentally friendly and efficient biochar adsorbents is crucial. Aquaculture by-product moss (bryophyte) was transformed into biochar, which can eliminate antibiotics from wastewater through adsorption.
View Article and Find Full Text PDFCalcif Tissue Int
January 2025
Orthopaedic Research Laboratory, Department of Orthopedic Surgery and Traumatology, Odense University Hospital & Department of Clinical Research, University of Southern Denmark, V18-812B-1, Etage 1, Bygning 45.4, Nyt Sund, SDU Campus 5230, Odense, Denmark.
There is an increasing demand for a suitable bone substitute to replace current clinical gold standard autografts or allografts. Majority of previous studies have focused on the early effects of substitutes on bone formation, while information on their long-term efficacies remains limited. This study investigated the efficacies of natural hydroxyapatite (nHA) derived from oyster shells and synthetic hydroxyapatite mixed with collagen (COL/HA) or chitosan (CS/HA) on bone regeneration and implant fixation in sheep.
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